Principles and applications of clinical mass spectrometry : small molecules, peptides, and pathogens /

Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens, derived from the Sixth Edition of the bestselling Tietz Textbook of Clinical Chemistry and Molecular Diagnostics is a concise resource for the quick implementation of mass spectrometry methods in cli...

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Bibliographic Details
Call Number:Libro Electrónico
Other Authors: Rifai, Nader (Editor), Horvath, Andrea R. (Andrea Rita) (Editor), Wittwer, C. (Carl), 1955- (Editor), Hoofnagle, Andy N. (associate editor.)
Format: Electronic eBook
Language:Inglés
Published: Amsterdam, Netherlands ; Oxford, United Kingdom ; Cambridge, MA, United States : Elsevier, [2018]
Subjects:
Mass spectrometry.
Clinical chemistry.
Mass Spectrometry
Chemistry, Clinical
Spectrom�etrie de masse.
Chimie clinique.
mass spectrometry.
SCIENCE > Chemistry > Analytic.
Clinical chemistry
Mass spectrometry
Online Access:Texto completo
Table of Contents:
  • Intro; Title page; Table of Contents; Copyright; Contributors; Preface; 1. Chromatography; Basic Principles of Chromatography; Gas Chromatography; Liquid Chromatography; Other Chromatographic Methods; 2. Mass Spectrometry; Basic Concepts and Definitions; Instrumentation; Clinical Applications; Optimization of Instrument Conditions; 3. Sample Preparation for Mass Spectrometry Applications; Background; General Techniques; Separation Techniques; Precipitation Techniques; Enrichment Techniques; Extraction Techniques; Chromatographic Techniques; Evolving Techniques
  • 4. Mass Spectrometry Applications in Infectious Disease and Pathogens IdentificationMatrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry; Analysis of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry Data; Electrospray Ionization Mass Spectrometry; Conclusions; 5. Development and Validation of Small Molecule Analytes by Liquid Chromatography-Tandem Mass Spectrometry; Practical Considerations for Liquid Chromatography-Tandem Mass Spectrometry Assays; Sample Preparation; 6. Proteomics; Historical Perspective; Biomarker Pipeline
  • Bottom-Up Targeted ProteomicsTop-Down Proteomics; Preanalytical and Other Technical Considerations; Conclusions; Index

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