Transporters in drug discovery and development : detailed concepts and best practice /

Bibliographic Details
Call Number:Libro Electrónico
Main Author: Lai, Yurong
Format: Electronic eBook
Language:Inglés
Published: Oxford : Elsevier Science, 2013.
Series:Woodhead Publishing series in biomedicine.
Subjects:
Biopharmaceutics.
Drug development.
Drugs > Design.
Biopharmaceutics
Drug Design
Biopharmacie.
M�edicaments > D�eveloppement.
M�edicaments > Conception.
MEDICAL > Pharmacology.
Drug development
Drugs > Design
Online Access:Texto completo
Table of Contents:
  • Membrane transporters and the diseases corresponding to functional defects
  • P-glycoprotein (P-gp/MDR1)/ABCB1
  • Multidrug resistanceassociated protein 2 (MRP2/ABCC2)
  • Breast cancer resistance protein (BCRP)/ABCG2
  • The bile salt export pump (BSEP/ABCB11)
  • Organic aniontransporting polypeptides (OATPs/SLCOs)
  • Organic anion, organic cation and zwitterion transporters of the SLC22 and SLC47 superfamily (OATs, OCTs, OCTNs and MATEs)
  • Drug transporters in drug discovery and development
  • 9 Transporter study methodologies.

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