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Tetramer Stability and Functional Regulation of Tumor Suppressor Protein p53
This thesis presents the first report of the comprehensive and quantitative analysis of the effects of tumor-derived mutations on the tetrameric structure of tumor suppressor protein p53, which plays a central role in maintaining genomic integrity. Inactivation of p53 via mutation of its gene is a k...
| Cote: | Libro Electrónico |
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| Format: | Électronique eBook |
| Langue: | Inglés |
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Tokyo :
Springer Japan : Imprint: Springer,
2012.
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| Édition: | 1st ed. 2012. |
| Collection: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Accès en ligne: | Texto Completo |