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Developments in T Cell Based Cancer Immunotherapies

This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects...

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Détails bibliographiques
Cote:Libro Electrónico
Collectivité auteur: SpringerLink (Online service)
Autres auteurs: Ascierto, Paolo A. (Éditeur intellectuel), Stroncek, David F. (Éditeur intellectuel), Wang, Ena (Éditeur intellectuel)
Format: Électronique eBook
Langue:Inglés
Publié: Cham : Springer International Publishing : Imprint: Humana, 2015.
Édition:1st ed. 2015.
Collection:Cancer Drug Discovery and Development,
Sujets:
Accès en ligne:Texto Completo
Table des matières:
  • 1 New insight of peptide vaccination in cancer immunotherapy
  • 2 The determinants of T cell function for effective anticancer vaccine
  • 3 T cell fate in the tumor microenvironment
  • 4 T cell receptor avidity and affinity and tumor specific TCR engineer
  • 5 Host genetic variation and somatic alteration associated with favorable or compromised T cell function
  • 6 Production of Clinical T Cell Therapies
  • 7 Clinical success of adoptive cell transfer therapy using tumor infiltrating lymphocytes.-8 Harnessing stem cell-like memory T cells for adoptive cell transfer therapy of cancer
  • 9 T cell blockade- anti-CTLA4 immunotherapy against cancer and Abscopal effect in combination therapy
  • 10 T cell modulation- anti-OD-1 antibodies for the treatment of cancer
  • 11 T cell based therapies in combination with other procedures
  • 12 Chimeric antigen receptor T cells CD19 CAR
  • 13 Hematopoietic Stem Cell transplantation as immune therapy of malignancies.