Clinical studies and therapies in Parkinson's disease : translations from preclinical models /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Segura-Aguilar, Juan
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2021.
Temas:
Parkinson's disease > Treatment.
Drugs > Testing.
Clinical Trials as Topic
Maladie de Parkinson > Traitement.
M�edicaments > Essais cliniques.
Drugs > Testing
Parkinson's disease > Treatment
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 1. Parkinson's disease; 2. Parkinson�s pharmacological therapy; 3. Dopamine synthesis; 4. Dopamine storage and release; 5. Dopamine oxidative deamination; 6. Dopamine methylation; 7. Dopamine oxidation to neuromelanin and neurotoxic metabolites; 8. Neuroprotective mechanisms against dopamine oxidation-dependent neurotoxicity; 9. Preclinical model based on exogenous neurotoxins for Parkinson's disease; 10. Preclinical models based on genetic mutations associated with the familial form of Parkinson�s disease; 11. Preclinical models based on endogenous neurotoxins; 12. Conclusions

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