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Cellular and animal models in human genomics research /
Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use o...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, United Kingdom :
Academic Press, an imprint of Elsvier,
[2019]
|
| Colección: | Translational and applied genomics series.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 003 | OCoLC | ||
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| 015 | |a GBB9D9083 |2 bnb | ||
| 019 | |a 1235832478 | ||
| 020 | |a 9780128165744 |q (electronic bk.) | ||
| 020 | |a 012816574X |q (electronic bk.) | ||
| 020 | |a 0128165731 | ||
| 020 | |a 9780128165737 | ||
| 020 | |z 9780128165737 |q (print) | ||
| 035 | |a (OCoLC)1112481122 |z (OCoLC)1235832478 | ||
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| 050 | 4 | |a QH430 |b .C45 2019 | |
| 060 | 4 | |a 2020 A-145 | |
| 060 | 4 | |a QU 460 | |
| 082 | 0 | 4 | |a 611.01816 |2 23 |
| 245 | 0 | 0 | |a Cellular and animal models in human genomics research / |c edited by Katherina Walz, Juan I. Young. |
| 264 | 1 | |a London, United Kingdom : |b Academic Press, an imprint of Elsvier, |c [2019] | |
| 300 | |a 1 online resource (228 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Translational and applied genomics | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from digital title page (viewed on November 12, 2019). | |
| 520 | |a Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth. Provides a thorough, accessible resource that helps researchers and students employ cellular and animal models in their own genetic and genomic studies Offers guidance on how to effectively interpret the results and significance of genetic and genomic model studies for human health Features chapters from international experts in the use of specific cellular and animal models, including yeast, worms, flies, fish, mice, and large animals, among other organisms | ||
| 650 | 0 | |a Human gene mapping. | |
| 650 | 0 | |a Animal models in research. | |
| 650 | 0 | |a Biological models. | |
| 650 | 0 | |a Genomics. | |
| 650 | 0 | |a Cytology |x Technique. | |
| 650 | 0 | |a Diseases |x Animal models. | |
| 650 | 1 | 2 | |a Genomics |0 (DNLM)D023281 |
| 650 | 2 | 2 | |a Cytological Techniques |0 (DNLM)D003584 |
| 650 | 2 | 2 | |a Models, Biological |0 (DNLM)D008954 |
| 650 | 2 | 2 | |a Disease Models, Animal |0 (DNLM)D004195 |
| 650 | 6 | |a Cartes chromosomiques humaines. |0 (CaQQLa)201-0214517 | |
| 650 | 6 | |a Mod�eles animaux dans la recherche. |0 (CaQQLa)201-0127335 | |
| 650 | 6 | |a Mod�eles biologiques. |0 (CaQQLa)201-0051425 | |
| 650 | 6 | |a G�enomique. |0 (CaQQLa)201-0363181 | |
| 650 | 6 | |a Cytologie |x Technique. |0 (CaQQLa)201-0005040 | |
| 650 | 6 | |a Maladies |x Mod�eles animaux. |0 (CaQQLa)201-0067878 | |
| 650 | 7 | |a Genomics |2 fast |0 (OCoLC)fst00940228 | |
| 650 | 7 | |a Diseases |x Animal models |2 fast |0 (OCoLC)fst00895160 | |
| 650 | 7 | |a Cytology |x Technique |2 fast |0 (OCoLC)fst00886306 | |
| 650 | 7 | |a Animal models in research |2 fast |0 (OCoLC)fst00809302 | |
| 650 | 7 | |a Biological models |2 fast |0 (OCoLC)fst00832276 | |
| 650 | 7 | |a Human gene mapping |2 fast |0 (OCoLC)fst00963066 | |
| 700 | 1 | |a Walz, Katherina, |e editor. | |
| 700 | 1 | |a Young, Juan I., |e editor. | |
| 776 | 0 | 8 | |i Print version: |a Walz, Katherina. |t Cellular and Animal Models in Human Genomics Research. |d San Diego : Elsevier Science & Technology, �2019 |z 9780128165737 |
| 830 | 0 | |a Translational and applied genomics series. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128165737 |z Texto completo |