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Halogenated biphenyls, terphenyls, naphthalenes, dibenzodioxins, and related products /

The chemical industry is increasingly faced with problems arizing from chemicals produced during the manufacture of halogenated biphenyls or phenols. Knowledge of these chemicals and their destructive properties is sporadic, and the acute toxicity of this group varies widely. This informative revise...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Kimbrough, Renate D., Jensen, Allan A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; New York : New York, NY, USA : Elsevier ; Sole distributors for the USA and Canada, Elsevier Science Pub. Co., 1989.
Edición:2nd fully rev. ed.
Colección:Topics in environmental health ; v. 4.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products; Copyright Page; Preface; Abbreviations; Table of contents; Part I: Chemistry, usage and environmental contamination; Chapter 1. Production, properties and usage of polychlorinated biphenyls; 1.1. Production; 1.2. Properties; 1.3. Applications and consumption; References; Appendix I; Chapter 2. Chemical properties, analytical methods and environmental levels of PCBs, PCTs, PCNs and PBBs; 2.1. Introduction; 2.2. Polychlorinated biphenyls; 2.3. Polychlorinated terphenyls (PCTs).
  • 2.4. Polychlorinated naphthalenes (PCNs)2.5. Polybrominated biphenyls (PBBs); References; Chapter 3. Chemical and physical properties, analytical methods, sources and environmental levels of halogenated dibenzodioxins and dibenzofurans; 3.1. Chemical and physical properties; 3.2. Analytical methods; 3.3. Sources of human exposure and environmental contamination; 3.4. Environmental levels; References; Chapter 4. Effects on fish and wildlife populations; 4.1. Introduction; 4.2. Case histories; 4.3. Discussion; Acknowledgements; References.
  • PART II: Toxicokinetics, in vitro tests, and animal toxicityChapter 5. Polyhalogenated aromatics: uptake, disposition and metabolism; 5.1. Introduction; 5.2. Absorption; 5.3. Disposition; 5.4. Fetal accumulation of halogenated aromatics; 5.5. Metabolism; Acknowledgements; References; Chapter 6. Acute and chronic toxicity and carcinogenesis in animals; 6.1. Introduction; 6.2. Toxicity; 6.3. Carcinogenesis; References; Chapter 7. Reproductive and developmental toxicity in animals; 7.1. Introduction; 7.2. Reproduction; 7.3. Developmental toxicity.
  • 7.4. Structure-activity and species considerationsReferences; Chapter 8. Genetic toxicity; 8.1. Introduction; 8.2. Polychlorinated biphenyls; 8.3. Polybrominated biphenyls; 8.4. Polychlorinated dibenzodioxins; 8.5. Polychlorinated naphthalenes; 8.6. Polychlorinated dibenzofurans; 8.7. Summary; Acknowledgement; References; Chapter 9. Mechanism of action and structure-activity relationships for the chlorinated dibenzo-p-dioxins and related compounds; 9.1. Introduction; 9.2. Evidence for a receptor; 9.3. Toxic effects of TCDD; 9.4. Biochemical effects of 2,3,7,8-TCDD and related compounds.
  • 9.5. Structure-activity relationships9.6. Summary; Acknowledgements; References; Chapter 10. Immune alterations; 10.1. Introduction; 10.2. The immune system; 10.3. Polychlorinated biphenyls (PCBs); 10.4. 2,3,7,8-TetrachIorodibenzo-p-dioxin (TCDD); 10.5. 2,3,7,8-Tetrachlorodibenzofuran (TCDF); 10.6. Polybrominated biphenyls (PBBs); 10.7. Mechanisms of immunotoxocity; 10.8. Conclusion; References; PART III: Human exposure and health effects; Chapter 11. General population exposure to environmental concentrations of halogenated biphenyls; 11.1 Introduction.