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Vitamins and hormones. advances in research and applications / Vol. 58 :
Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. First published in 1943, Vitamins and H...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
2000.
|
| Colección: | Vitamins and hormones ;
v. 58. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Vitamins and hormones. |n Vol. 58 : |b advances in research and applications / |c editor-in-chief, Gerald Litwack. |
| 260 | |a San Diego : |b Academic Press, |c 2000. | ||
| 300 | |a 1 online resource (xiii, 505 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Vitamins and hormones, |x 0083-6729 ; |v v. 58 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Now, new discoveries have proved that several of the vitamins function as hormones and many of the substances inferred by the title of the serial function in signal transduction processes. Accordingly, the Editor-in-Chief has expanded the scope of the serial to reflect this newer understanding of function-structure relationships in cellular communication. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. | ||
| 505 | 0 | |a Front Cover; Vitamins and Hormones; Copyright Page; Contents; Preface; Chapter 1. Protein Folding and Deficiencies Caused by Dominant-Negative Mutants of Hormones; I. Introduction; II. Functions of the Endoplasmic Reticulum Related to Protein Folding; III. Aspects of the Neuroendocrine Secretory Pathway; IV. Isolated Dominant-Negative Hormone Deficiency: Problems in the Secretory Pathway; V. Conclusions; References; Chapter 2. Structural Aspects of the G-Protein Receptor, Rhodopsin; I. Introduction; II. Seven Transmembrane Helical Hydrophobic Core of Rhodopsin | |
| 505 | 8 | |a III. Structure of the Retinal and Its Binding Site in RhodopsinIV. Structure of Extramembranous Domains of Rhodopsin; V. Cytoplasmic Face of Rhodopsin; VI. Intradiskal Face of Rhodopsin; VII. Future Directions; References; Chapter 3. Molecular Modeling of Mammalian Cytochromes P450: Application to Study Enzyme Function; I. Introduction; II. Molecular Modeling Methods; III. Homology Models in Studies of P450 Function; IV. Perspectives and Conclusions; References; Chapter 4. Prostaglandin D Synthase: Structure and Function; I. Introduction | |
| 505 | 8 | |a II. Pharmacologic Actions of Prostaglandin D2 and Its MetabolitesIII. Lipocalin-Type Prostaglandin D Synthase ( �-Trace); IV. Hematopoietic Prostaglandin D Synthase; V. Future Studies; References; Chapter 5. Steroid Dehydrogenase Structures, Mechanism of Action, and Disease; I. Introduction; II. 3a,20� -Hydroxysteroid Dehydrogenase; III. Aldosterone, Cortisol, Licorice, and Hypertension; IV. 17� -Hydroxysteroid Dehydrogenase, Inhibitors, and Cancer; V. Protein Sequence and Three-Dimensional Conformation; VI. Conclusions; References; Chapter 6. Structure-Based Inhibitor Design; I. Introduction | |
| 505 | 8 | |a II. Target Selection, Cloning, and Determination of 3-D StructuresIII. Crystallographic Water Molecules; IV. Computational Approaches to Lead Compound Discovery; V. Estimating the Theoretical Limits for Reversible Inhibitor Binding; VI. Connectivity, Flexibility, and Conformational Entropy; VII. Using Enzyme Structures in Dealing with Resistance Mutations; VIII. Conclusions; References; Chapter 7. Protein Folding Using Contact Maps; I. Introduction; II. Structure Representation; III. The Reconstruction Procedure; IV. Dynamics in Contact Map Space; V. Approximation for Free Energy; VI. Results | |
| 505 | 8 | |a VII. ConclusionsReferences; Chapter 8. HIV Protease: Enzyme Function and Drug Resistance; I. Introduction; II. HIV PR Is a Member of the Aspartic Proteinase Family; III. HIV PR Structure; IV. Mechanism of the Substrate Cleavage and Protonation State of the Catalytic Aspartates; V. Substrate Specificity; VI. Assay Methods; VII. pH Optima; VIII. Dimer Stability; IX. Thermodynamic Characteristics of Inhibitor Binding; X. Inhibitors of HIV PR; XI. Introduction to Resistance to HIV PR Inhibitors; XII. Active Site Mutations; XIII. Nonactive Site Mutations; XIV. Cleavage Site Mutants | |
| 546 | |a English. | ||
| 650 | 0 | |a Vitamins. | |
| 650 | 0 | |a Hormones. | |
| 650 | 0 | |a Steroid hormones. | |
| 650 | 0 | |a Peptide hormones. | |
| 650 | 0 | |a Vitamins |x Research. | |
| 650 | 0 | |a Sterol hormones. | |
| 650 | 6 | |a Vitamines. |0 (CaQQLa)201-0018178 | |
| 650 | 6 | |a Hormones. |0 (CaQQLa)201-0017163 | |
| 650 | 6 | |a Hormones st�ero�ides. |0 (CaQQLa)201-0023585 | |
| 650 | 6 | |a Hormones peptidiques. |0 (CaQQLa)201-0023590 | |
| 650 | 7 | |a hormone. |2 aat |0 (CStmoGRI)aat300265405 | |
| 650 | 7 | |a Sterol hormones |2 fast |0 (OCoLC)fst01133281 | |
| 650 | 7 | |a Hormones |2 fast |0 (OCoLC)fst00960219 | |
| 650 | 7 | |a Peptide hormones |2 fast |0 (OCoLC)fst01057558 | |
| 650 | 7 | |a Steroid hormones |2 fast |0 (OCoLC)fst01133262 | |
| 650 | 7 | |a Vitamins |2 fast |0 (OCoLC)fst01168236 | |
| 650 | 7 | |a Vitamins |x Research |2 fast |0 (OCoLC)fst01168243 | |
| 700 | 1 | |a Litwack, Gerald. | |
| 776 | |z 0-12-709858-5 | ||
| 830 | 0 | |a Vitamins and hormones ; |v v. 58. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780127098586 |z Texto completo |