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Horizons in cancer research. Volume 42 /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Watanabe, Hiroto S.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Science, Ã2011.
Colección:Horizons in cancer research ; 42.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • HORIZONS IN CANCER RESEARCH. VOLUME 42; HORIZONS IN CANCER RESEARCH. VOLUME 42 ; Contents ; Preface ; Signaling Pathways as Biomarkers in Human Renal Cell Carcinoma ; Summary ; Introduction ; Carbonic Anhydrase 9 ; GLUT Transporters ; Conclusion ; Acknowledgments ; References ; Role of Prostate-Specific Antigen (PSA) in Pathological Angiogenesis and Prostate Tumor Growth ; Abstract ; Conclusion ; Acknowledgments ; References ; Elapsed Times in the Management of Early Stage Breast Cancer ; Abstract ; Introduction ; Detection to Treatment ; Detection to Diagnosis.
  • Detection to Surgery Surgery to Chemotherapy ; Surgery to Radiotherapy ; Summary & Caveats ; What are the predictors of longer elapsed times in Canada? ; Detection to Diagnosis ; Detection to Surgery ; Surgery to Chemotherapy ; Surgery to Radiotherapy ; Summary & Caveats ; A multi-interval multi-resolution analytics framework ; Conclusions ; Acknowledgments ; References ; Positional Cloning of Tumor Suppressor Genes from 3p21.3 Involved in Major Human Cancers ; 1. Abstract ; 2. Introduction ; 3. Results.
  • A) Localization of Critical Regions on the Short Arm of Chromosome 3 Using Allelotyping of the Dense Set of Polymorphic Markers Multiple interstitial deletions were found in prevalence to terminal deletions in 3p in five epithelial tumor types ; Chromosome 3p "hot spots" affected in major epithelial tumors ; Contribution of amplification events in allelic alterations of 3p microsatellites ; Correlation of 3p allelic alterations with tumor progression ; b) Careful Mapping of LUCA and AP20 Regions Using Real Time Quantitative PCR ; QPCR for detection copy number changes.
  • QPCR results for RCC, BC and SCLC tumor samples and cell lines Comparison of LOH and QPCR data. fine deletion mapping of homozygous deletions ; Complex 3p rearrangements in major epithelial cancers ; c) NotI-Microarrays to Identify Cancer Causing Genes and Develop Biomarkers for Early Diagnosis, Prognosis and Prediction of Major Types of Cancer ; d) Identification of Novel Tumor Suppressor Genes ; Conclusion ; Acknowledgments ; References ; Novel Methylation-Dependent Markers/Tumor Suppressor Genes Involved in the Development of Renal Cell Cancer ; Abstract ; Introduction.
  • RCC Methylation Profiles of RASSF1A, SEMA3B, RARbeta2, RHOA, GPX1, USP4 Genes Genes in the LUCA Critical Region (3p21.31) ; Genes from the Distal 3p Region (3p26-P22) ; RCC Specific Methylation Profile for Six 3p Genes ; Methylation Pattern of RASSF1A, RAR-Beta2, SEMA3B, GPX1 and Tumor Progression ; Expression Profiles of Cancer Associated Genes: RBSP3, SEMA3B, SEMA3F, NPRL2, HYAL1, HYAL2, ITGA9, VILL, CHL1, and ACY1 in RCC ; High Mutation Frequency of the Tumor Suppressors RASSF1 and RBSP3 (CTDSPL) in RCC ; NotI Microarrays for Identification of RCC Biomarkers ; Conclusion.