Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization /

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Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasin...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Kerns, Edward Harvel
Otros Autores: Di, Li
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press, ©2008.
Colección:Drug Discovery Bundle.
Temas:
Pharmaceutical chemistry.
Drugs > Structure-activity relationships.
Drug development.
Drugs > Design.
Drugs > Side effects.
Pharmacokinetics.
Structure-activity relationships (Biochemistry)
Drug Design
Chemistry, Pharmaceutical
Drug Evaluation, Preclinical
Drug-Related Side Effects and Adverse Reactions
Pharmaceutical Preparations > metabolism
Pharmacokinetics
Structure-Activity Relationship
Chimie pharmaceutique.
Médicaments > Relations structure-activité.
Médicaments > Développement.
Médicaments > Conception.
Médicaments > Effets secondaires.
Pharmacocinétique.
Relations structure-activité (Biochimie)
MEDICAL > Drug Guides.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
MEDICAL > Nursing > Pharmacology.
Drugs > Side effects
Drug development
Drugs > Design
Drugs > Structure-activity relationships
Pharmaceutical chemistry
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