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A Prescription for Change : The Looming Crisis in Drug Development /

The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes -- and indeed because of them -- our ability to deliver new medicines may be quickly co...

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Detalles Bibliográficos
Autor principal: Kinch, Michael, 1966- (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Chapel Hill : The University of North Carolina Press, 2016.
Colección:Book collections on Project MUSE.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Kinch, Michael,  |d 1966-  |e author. 
245 1 2 |a A Prescription for Change :   |b The Looming Crisis in Drug Development /   |c Michael S. Kinch. 
264 1 |a Chapel Hill :  |b The University of North Carolina Press,  |c 2016. 
264 3 |a Baltimore, Md. :  |b Project MUSE,   |c 2017 
264 4 |c ©2016. 
300 |a 1 online resource (352 pages). 
336 |a text  |b txt  |2 rdacontent 
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490 0 |a The Luther H. Hodges Jr. and Luther H. Hodges Sr. series on business, entrepreneurship, and public policy 
505 0 |a Introduction: How Did We Reach This Point? -- Why Regulate Medicines? -- Trials and Tribulations -- Dreams of Greatness: The Birth of the Pharmaceutical Industry -- Triumph and Tragedy -- Ivory Tower of Power -- The DNA of Biotechnology -- Blockbusters and Bombs: Pressures on the Pharmaceutical Industry -- Sea Monsters, Immunauts, and Death Panels -- Drama on the I-270 Tech Corridor -- Autophagy -- Three Views of a Train Wreck -- Bridging the Valley. 
520 |a The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes -- and indeed because of them -- our ability to deliver new medicines may be quickly coming to an end. Moving from the beginning of the twentieth century to the present, A Prescription for Change reveals how changing business strategies combined with scientific hubris have altered the way new medicines are discovered, with dire implications for both health and the economy. To explain how we have arrived at this pivotal moment, Michael Kinch recounts the history of pharmaceutical and biotechnological advances in the twentieth century. Kinch relates stories of the individuals and organizations that built the modern infrastructure that supports the development of innovative new medicines. He shows that an accelerating cycle of acquisition and downsizing is cannibalizing that infrastructure Kinch demonstrates the dismantling of the pharmaceutical and biotechnological research and development enterprises could also provide opportunities to innovate new models that sustain and expand the introduction of newer and better breakthrough medicines in the years to come. - Publisher. 
588 |a Description based on print version record. 
650 7 |a Pharmaceutical industry.  |2 fast  |0 (OCoLC)fst01060129 
650 7 |a Drugs  |x Research  |x Economic aspects.  |2 fast  |0 (OCoLC)fst00898899 
650 7 |a Drug development.  |2 fast  |0 (OCoLC)fst00898670 
650 7 |a Drugs  |x Design.  |2 fast  |0 (OCoLC)fst00898790 
650 7 |a BUSINESS & ECONOMICS  |x Development  |x Business Development.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 6 |a Medicaments  |x Conception. 
650 6 |a Industrie pharmaceutique. 
650 6 |a Medicaments  |x Recherche  |x Aspect economique. 
650 6 |a Medicaments  |x Developpement. 
650 2 |a Drug Industry 
650 2 |a Drug Design 
650 0 |a Drugs  |x Design. 
650 0 |a Pharmaceutical industry. 
650 0 |a Drugs  |x Research  |x Economic aspects. 
650 0 |a Drug development. 
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830 0 |a Book collections on Project MUSE. 
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945 |a Project MUSE - 2017 Complete 
945 |a Project MUSE - 2017 Political Science and Policy Studies