Epigenetic cancer therapy /

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Gray, Steven G. (Thoracic oncology researcher) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Academic Press, 2023.
Edición:Second edition.
Colección:Translational epigenetics series.
Temas:
Cancer > Genetic aspects.
Cancer > Treatment.
Epigenesis.
Neoplasms > genetics
Epigenesis, Genetic
Neoplasms > therapy
Genetic Therapy
Cancer > Aspect g�en�etique.
Cancer > Traitement.
�Epig�en�ese.
Th�erapie g�enique.
Cancer > Genetic aspects
Cancer > Treatment
Epigenesis
Acceso en línea:Texto completo
Tabla de Contenidos:
  • <P>1. Introduction</p> <p><b>Part 1: Introduction and Key Concepts</b> 2. DNA Methylation and Hydroxymethylation in Cancer 3. Writers, Readers, and Erasers of Epigenetic Marks 4. Oncohistones 5. MicroRNAs, epi-miRNAs and Cancer 6. Long Noncoding RNAs and Cancer 7. The Epitranscriptome 8. Mining the Epigenetic Landscape: Surface Mining or Deep Underground - Alecsandar Milosavljevic 9: Epigenetics Clocks: Concepts for Carcinogenesis10: Environmental Pollution Epigenetics and Cancer</p> <p><b>Part 2: Epigenetics and Cancer</b> 11. Development of Epigenetic Targeted Therapies in Hematological Malignancies: From Serendipity to Synthetic Lethality 12. Epigenetic Therapy in Lung Cancer 13. Breast Cancer Epigenetics 14. Therapeutic Applications of the Prostate Cancer Epigenome 15. Neuroblastoma</p> <p><b>Part 3: Targeting Aberrant Epigenetics</b> 16. Nutritional Epigenetic Regulators in the Field of Cancer: New Avenues for Chemopreventive Approaches
  • 17. Emerging Epigenetic Therapies- Lysine Methyltransferase/PRC Complex Inhibitors 18. Inhibitors of Jumonji C-Domain Histone Demethylases 19. Emerging Epigenetic Therapies: Lysine Acetyltransferase Inhibitors 20: Histone Deacetylases 21. Emerging Epigenetic Therapies</p> <p><b>Part 4: Issues to Overcome/Areas of Concern</b> 22. Genetic Intratumoral Heterogeneity 23. Challenges for single cell epigenetic analysis 24. Epigenetics Underpinning DNA Damage Repair 25. Epigenetics of Cisplatin Resistance 26. Therapeutically Targeting Epigenetic Regulation of Cancer Stem Cells </p> <p><b>Part 5: Future Directions: Translation to the Clinic</b> 27. Personalized Epigenetic Therapy-Chemosensitivity Testing 28. Personalized Therapy-Epigenetic Profiling as Predictors of Prognosis and Response 29. Epigenetic Priming - Fact or Fallacy 30. CRISPR and epigenetics 31. Epigenetics and CAR-T </p>

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