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|a 9780323917155
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|2 23/eng/20230523
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|a Epigenetic cancer therapy /
|c edited by Steven Gray.
|
250 |
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|a Second edition.
|
264 |
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1 |
|a Amsterdam :
|b Academic Press,
|c 2023.
|
300 |
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|a 1 online resource (xxv, 745 pages) :
|b illustrations
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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|a Translational epigenetics series
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504 |
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|a Includes bibliographical references and index.
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588 |
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|a Print version record.
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|a <P>1. Introduction</p> <p><b>Part 1: Introduction and Key Concepts</b> 2. DNA Methylation and Hydroxymethylation in Cancer 3. Writers, Readers, and Erasers of Epigenetic Marks 4. Oncohistones 5. MicroRNAs, epi-miRNAs and Cancer 6. Long Noncoding RNAs and Cancer 7. The Epitranscriptome 8. Mining the Epigenetic Landscape: Surface Mining or Deep Underground - Alecsandar Milosavljevic 9: Epigenetics Clocks: Concepts for Carcinogenesis10: Environmental Pollution Epigenetics and Cancer</p> <p><b>Part 2: Epigenetics and Cancer</b> 11. Development of Epigenetic Targeted Therapies in Hematological Malignancies: From Serendipity to Synthetic Lethality 12. Epigenetic Therapy in Lung Cancer 13. Breast Cancer Epigenetics 14. Therapeutic Applications of the Prostate Cancer Epigenome 15. Neuroblastoma</p> <p><b>Part 3: Targeting Aberrant Epigenetics</b> 16. Nutritional Epigenetic Regulators in the Field of Cancer: New Avenues for Chemopreventive Approaches -- 17. Emerging Epigenetic Therapies- Lysine Methyltransferase/PRC Complex Inhibitors 18. Inhibitors of Jumonji C-Domain Histone Demethylases 19. Emerging Epigenetic Therapies: Lysine Acetyltransferase Inhibitors 20: Histone Deacetylases 21. Emerging Epigenetic Therapies</p> <p><b>Part 4: Issues to Overcome/Areas of Concern</b> 22. Genetic Intratumoral Heterogeneity 23. Challenges for single cell epigenetic analysis 24. Epigenetics Underpinning DNA Damage Repair 25. Epigenetics of Cisplatin Resistance 26. Therapeutically Targeting Epigenetic Regulation of Cancer Stem Cells </p> <p><b>Part 5: Future Directions: Translation to the Clinic</b> 27. Personalized Epigenetic Therapy-Chemosensitivity Testing 28. Personalized Therapy-Epigenetic Profiling as Predictors of Prognosis and Response 29. Epigenetic Priming - Fact or Fallacy 30. CRISPR and epigenetics 31. Epigenetics and CAR-T </p>
|
650 |
|
0 |
|a Cancer
|x Genetic aspects.
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650 |
|
0 |
|a Cancer
|x Treatment.
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650 |
|
0 |
|a Epigenesis.
|
650 |
|
2 |
|a Neoplasms
|x genetics
|0 (DNLM)D009369Q000235
|
650 |
|
2 |
|a Epigenesis, Genetic
|0 (DNLM)D044127
|
650 |
|
2 |
|a Neoplasms
|x therapy
|0 (DNLM)D009369Q000628
|
650 |
|
2 |
|a Genetic Therapy
|0 (DNLM)D015316
|
650 |
|
6 |
|a Cancer
|x Aspect g�en�etique.
|0 (CaQQLa)201-0004687
|
650 |
|
6 |
|a Cancer
|x Traitement.
|0 (CaQQLa)201-0004693
|
650 |
|
6 |
|a �Epig�en�ese.
|0 (CaQQLa)201-0066257
|
650 |
|
6 |
|a Th�erapie g�enique.
|0 (CaQQLa)201-0193146
|
650 |
|
7 |
|a Cancer
|x Genetic aspects
|2 fast
|0 (OCoLC)fst00845368
|
650 |
|
7 |
|a Cancer
|x Treatment
|2 fast
|0 (OCoLC)fst00845538
|
650 |
|
7 |
|a Epigenesis
|2 fast
|0 (OCoLC)fst00914128
|
700 |
1 |
|
|a Gray, Steven G.
|c (Thoracic oncology researcher),
|e editor.
|
776 |
0 |
8 |
|i Print version:
|t Epigenetic cancer therapy.
|b Second edition.
|d Amsterdam : Academic Press, 2023
|z 9780323913676
|w (OCoLC)1372469054
|
830 |
|
0 |
|a Translational epigenetics series.
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780323913676
|z Texto completo
|