Mitochondria and bacterial pathogens. Part A /

Mitochondria and Bacterial Pathogens, Volume 374, Part A. Mitochondria control various processes that are integral to cellular and organismal homeostasis, including Ca2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not surprisingly, multiple pathogenic bacteria have evolved strategies to...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Marchi, Saverio, Galluzzi, Lorenzo
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, MA : Academic Press, 2023.
Colección:International review of cell and molecular biology ; v. 374.
Temas:
Mitochondria.
Pathogenic bacteria.
Mitochondries.
Bact�eries pathog�enes.
Mitochondria
Pathogenic bacteria
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Mitochondria and Bacterial Pathogens Part A
  • Copyright
  • Contents
  • Contributors
  • Chapter One: The bacterial origin of mitochondria: Incorrect phylogenies and the importance of metabolic traits
  • 1. Introduction
  • 2. Impact of mass extinction events on the evolution of animals and their mitochondria
  • 3. Syntrophic models for eukaryogenesis and their metabolic implications
  • 3.1. Sulfur oxidation
  • 3.2. Hydrogen-producing hydrogenase
  • 4. The aerobic ancestry of mitochondria: Systems for cytochrome c biogenesis
  • 5. Incorrect phylogenies of proteins shared by bacteria and mitochondria
  • 6. Was the ancestor of mitochondria photosynthetic?
  • 7. Was the ancestor of mitochondria a facultative or obligate aerobe?
  • 8. Conclusion
  • Acknowledgments
  • References
  • Chapter Two: Legionella and mitochondria, an intriguing relationship
  • 1. Introduction
  • 2. The dynamic contacts between mitochondria and Legionella-containing phagosomes
  • 3. Regulation of mitochondrial functions by L. pneumophila with metabolic consequences
  • 4. Regulation of mitochondria during L. pneumophila infection allows to bypass cell-autonomous immunity and to control ho ...
  • 4.1. Reactive oxygen species (ROS), mitochondrial ROS (mROS) and inflammasome-mediated pyroptosis
  • 4.2. Modulation of autophagy at mitochondrial-associated ER contacts by L. pneumophila
  • 4.3. Modulation of the mitochondrial-apoptotic pathway during L. pneumophila infection
  • 5. Conclusions
  • Acknowledgments
  • References
  • Chapter Three: Role of mitochondrial outer membrane permeabilization during bacterial infection
  • 1. Introduction
  • 2. Mitochondria: Organization and function
  • 3. Relevance of mitochondria in the context of bacterial infection
  • 4. Apoptosis and its players
  • 5. Mitochondrial outer membrane permeabilization (MOMP).
  • 6. Incomplete MOMP and sub-lethal signals in the mitochondrial apoptosis machinery
  • 7. Modulation of mitochondrial apoptosis by bacterial infection
  • 8. Induction of MOMP by individual pathogenic bacteria
  • 9. Induction of sub-lethal signals by infection
  • 10. Inhibition of MOMP by individual pathogenic bacteria
  • 11. Concluding remarks
  • References
  • Chapter Four: The interplay between selective types of (macro)autophagy: Mitophagy and xenophagy
  • 1. Introduction
  • 1.1. Autophagy
  • 1.2. Mitophagy
  • 1.3. Xenophagy
  • 2. Xenophagy and mitophagy act through common molecular mechanisms
  • 2.1. Autophagy receptors
  • 2.2. E3 ligases
  • 3. Immunity and disease
  • 3.1. Xenophagy and mitophagy cooperate in pathogen elimination and generation of antigens for adaptive immunity activation
  • 3.2. Pathogens promote mitophagy to limit xenophagy
  • 3.3. Autophagy and mitophagy play a key role in development
  • 3.4. Autophagy and mitophagy affect carcinogenesis
  • 3.5. Autophagy and mitophagy regulate metabolism, and vice versa
  • 4. Conclusions
  • Acknowledgments
  • Declarations
  • References
  • Chapter Five: Role of mitochondria in regulating immune response during bacterial infection
  • 1. Introduction
  • 2. Mitochondria and metabolism
  • 2.1. Oxidative phosphorylation
  • 2.2. TCA cycle
  • 2.3. Pyruvate
  • 2.4. Citrate
  • 2.5. Fumarate
  • 2.6. Itaconate
  • 2.7. Succinate
  • 3. Mitochondrial dynamics and molecular machineries
  • 3.1. Biogenesis
  • 3.2. Mitochondrial fusion
  • 3.3. Mitochondrial fission
  • 3.4. Mitophagy
  • 3.5. Movement/transport
  • 4. Mitochondria mediated immune pathways
  • 4.1. mitoROS
  • 4.2. mtDNA
  • 4.3. NLRP3
  • 4.4. MAVS
  • 5. Mitochondria mediated cell death and ATP generation
  • 6. Mitochondria regulating immune functions against specific bacterial infections
  • 6.1. Salmonella typhimurium
  • 6.2. Shigella.
  • 6.3. Mycobacterium
  • 6.4. Helicobacter
  • 6.5. Vibrio cholerae
  • 6.6. Legionella pneumophila
  • 6.7. Chlamydia
  • 6.8. Pseudomonas
  • 6.9. Listeria
  • 6.10. Staphylococcus
  • 6.11. E. coli
  • 6.12. Coxiella burnetii
  • 7. Crosstalk between microbiome and mitochondria
  • 8. Mitochondria centric therapeutics against bacterial infection
  • 9. Conclusion and future direction
  • Acknowledgments
  • References.

Ejemplares similares