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|a 571.657
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|a Mitochondria and bacterial pathogens.
|n Part A /
|c edited by Saverio Marchi, Lorenzo Galluzzi.
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|a Cambridge, MA :
|b Academic Press,
|c 2023.
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|a 1 online resource
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|b txt
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|a International review of cell and molecular biology ;
|v v. 374
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|a Print version record.
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|a Intro -- Mitochondria and Bacterial Pathogens Part A -- Copyright -- Contents -- Contributors -- Chapter One: The bacterial origin of mitochondria: Incorrect phylogenies and the importance of metabolic traits -- 1. Introduction -- 2. Impact of mass extinction events on the evolution of animals and their mitochondria -- 3. Syntrophic models for eukaryogenesis and their metabolic implications -- 3.1. Sulfur oxidation -- 3.2. Hydrogen-producing hydrogenase -- 4. The aerobic ancestry of mitochondria: Systems for cytochrome c biogenesis -- 5. Incorrect phylogenies of proteins shared by bacteria and mitochondria -- 6. Was the ancestor of mitochondria photosynthetic? -- 7. Was the ancestor of mitochondria a facultative or obligate aerobe? -- 8. Conclusion -- Acknowledgments -- References -- Chapter Two: Legionella and mitochondria, an intriguing relationship -- 1. Introduction -- 2. The dynamic contacts between mitochondria and Legionella-containing phagosomes -- 3. Regulation of mitochondrial functions by L. pneumophila with metabolic consequences -- 4. Regulation of mitochondria during L. pneumophila infection allows to bypass cell-autonomous immunity and to control ho ... -- 4.1. Reactive oxygen species (ROS), mitochondrial ROS (mROS) and inflammasome-mediated pyroptosis -- 4.2. Modulation of autophagy at mitochondrial-associated ER contacts by L. pneumophila -- 4.3. Modulation of the mitochondrial-apoptotic pathway during L. pneumophila infection -- 5. Conclusions -- Acknowledgments -- References -- Chapter Three: Role of mitochondrial outer membrane permeabilization during bacterial infection -- 1. Introduction -- 2. Mitochondria: Organization and function -- 3. Relevance of mitochondria in the context of bacterial infection -- 4. Apoptosis and its players -- 5. Mitochondrial outer membrane permeabilization (MOMP).
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|a 6. Incomplete MOMP and sub-lethal signals in the mitochondrial apoptosis machinery -- 7. Modulation of mitochondrial apoptosis by bacterial infection -- 8. Induction of MOMP by individual pathogenic bacteria -- 9. Induction of sub-lethal signals by infection -- 10. Inhibition of MOMP by individual pathogenic bacteria -- 11. Concluding remarks -- References -- Chapter Four: The interplay between selective types of (macro)autophagy: Mitophagy and xenophagy -- 1. Introduction -- 1.1. Autophagy -- 1.2. Mitophagy -- 1.3. Xenophagy -- 2. Xenophagy and mitophagy act through common molecular mechanisms -- 2.1. Autophagy receptors -- 2.2. E3 ligases -- 3. Immunity and disease -- 3.1. Xenophagy and mitophagy cooperate in pathogen elimination and generation of antigens for adaptive immunity activation -- 3.2. Pathogens promote mitophagy to limit xenophagy -- 3.3. Autophagy and mitophagy play a key role in development -- 3.4. Autophagy and mitophagy affect carcinogenesis -- 3.5. Autophagy and mitophagy regulate metabolism, and vice versa -- 4. Conclusions -- Acknowledgments -- Declarations -- References -- Chapter Five: Role of mitochondria in regulating immune response during bacterial infection -- 1. Introduction -- 2. Mitochondria and metabolism -- 2.1. Oxidative phosphorylation -- 2.2. TCA cycle -- 2.3. Pyruvate -- 2.4. Citrate -- 2.5. Fumarate -- 2.6. Itaconate -- 2.7. Succinate -- 3. Mitochondrial dynamics and molecular machineries -- 3.1. Biogenesis -- 3.2. Mitochondrial fusion -- 3.3. Mitochondrial fission -- 3.4. Mitophagy -- 3.5. Movement/transport -- 4. Mitochondria mediated immune pathways -- 4.1. mitoROS -- 4.2. mtDNA -- 4.3. NLRP3 -- 4.4. MAVS -- 5. Mitochondria mediated cell death and ATP generation -- 6. Mitochondria regulating immune functions against specific bacterial infections -- 6.1. Salmonella typhimurium -- 6.2. Shigella.
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|a 6.3. Mycobacterium -- 6.4. Helicobacter -- 6.5. Vibrio cholerae -- 6.6. Legionella pneumophila -- 6.7. Chlamydia -- 6.8. Pseudomonas -- 6.9. Listeria -- 6.10. Staphylococcus -- 6.11. E. coli -- 6.12. Coxiella burnetii -- 7. Crosstalk between microbiome and mitochondria -- 8. Mitochondria centric therapeutics against bacterial infection -- 9. Conclusion and future direction -- Acknowledgments -- References.
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|a Mitochondria and Bacterial Pathogens, Volume 374, Part A. Mitochondria control various processes that are integral to cellular and organismal homeostasis, including Ca2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not surprisingly, multiple pathogenic bacteria have evolved strategies to subvert mitochondrial functions in support of their survival and dissemination. In the IRCMB volume 375, the authors discus different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. Collection of articles reporting the role of mitochondria during bacterial infection Mitochondria, the evolutionary successors of an ancient endosymbiotic prokaryote, occupy a central position in the biology of modern eukaryotic cells Numerous pathogenic bacteria have evolved strategies to subvert the mitochondrial functions of host cells in support of proliferation and dissemination.
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|a Mitochondria.
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|a Pathogenic bacteria.
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|a Mitochondries.
|0 (CaQQLa)201-0015242
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|a Bact�eries pathog�enes.
|0 (CaQQLa)201-0004317
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|a Mitochondria
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|a Pathogenic bacteria
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|0 (OCoLC)fst01054930
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|a Marchi, Saverio.
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|a Galluzzi, Lorenzo.
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|i Print version:
|z 0323994032
|z 9780323994033
|w (OCoLC)1342621833
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|a International review of cell and molecular biology ;
|v v. 374.
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|u https://sciencedirect.uam.elogim.com/science/bookseries/19376448/374
|z Texto completo
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