Advances in genetics. Volume 110 /

Bibliographic Details
Call Number:Libro Electrónico
Other Authors: Maloy, Stanley R. (Editor), Hughes, Kelly Thomas (Editor)
Format: Electronic eBook
Language:Inglés
Published: Cambridge, MA : Academic Press, 2022.
Subjects:
Genetics.
G�en�etique.
genetics.
Genetics
Online Access:Texto completo
Table of Contents:
  • Genetic factors governing bacterial virulence and host plant susceptibility during Agrobacterium infection / Benoit Lacroix and Vitaly Citovsky
  • Epigenetic regulation of angiogenesis in tumor progression / Vanessa Desantis, Antonio G. Solimando, and Domenico Ribatti.
  • Intro
  • Advances in Genetics
  • Copyright
  • Contents
  • Contributors
  • Chapter One: RecBCD enzyme and Chi recombination hotspots as determinants of self vs. non-self: Myths and mechanisms
  • 1. Introduction
  • 2. Chi is more frequent in many bacterial species and E. coli phages and plasmids than in E. coli itself
  • 3. Chi is active in ``foreign�� species
  • 4. Is Chi ``over-represented�� in E. colis genome?
  • 4.1. Nucleotides are not randomly arranged in the E. coli genome
  • 4.2. Amino acids are not quite randomly associated in E. coli proteins
  • 4.3. Codon usage is even more non-random than amino acid usage in E. coli
  • 4.4. Preferential codon usage can account for Chi�s high frequency in E. coli
  • 5. ``Chi�� sequence of S. aureus also comports with its codon usage
  • 6. Temperate phage P1 contains 50 Chi sites, likely uses them to its advantage, and appears to select for Chi as a recomb ...
  • 7. A myth: ``Chi converts RecBCD from phage destruction to DNA repair��
  • 8. An observation: RecBCD destroys DNA in E. coli only if it cannot recombine
  • 9. Mechanisms employing RecBCD that do distinguish self vs. non-self DNA
  • 10. Conclusion: Telling self from non-self is complex
  • 11. Methods of data analysis
  • Acknowledgments
  • References
  • Chapter Two: Multiple regulatory mechanisms for pH homeostasis in the gastric pathogen, Helicobacter pylori
  • 1. Introduction
  • 1.1. Two mechanisms of acid-resistance
  • 1.2. Urease activity needs to be regulated
  • 2. H. pylori reference genome, gene nomenclature and genomic diversity
  • 3. Urease function and urea supply
  • 4. Regulation of urease activities
  • 4.1. Sensors of pH changes
  • 4.2. Effectors controlling the expression of the urease gene cluster
  • 4.3. Nickel homeostasis and urease activation
  • 4.3.1. Nickel importing and exporting.
  • 4.3.2. Nickel sequestrating and storage proteins
  • 4.3.3. Different pathways for nickel insertion between urease and hydrogenase
  • 4.3.4. Regulatory proteins for maintaining nickel homeostasis
  • Acknowledgments
  • References.

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