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SCIDIR_on1288213769 |
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20231120010624.0 |
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211211t20222022ne a ob 001 0 eng d |
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|a EBLCP
|b eng
|e rda
|e pn
|c EBLCP
|d YDX
|d EBLCP
|d OPELS
|d GZM
|d OCLCO
|d OCLCF
|d TFW
|d SFB
|d OCLCQ
|d OCLCO
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066 |
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|c (S
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019 |
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|a 1287200736
|a 1287209172
|a 1287237397
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|a 9780323903639
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|a 0323903630
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|z 9780323854795
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|a (OCoLC)1288213769
|z (OCoLC)1287200736
|z (OCoLC)1287209172
|z (OCoLC)1287237397
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4 |
|a QC463.I44
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082 |
0 |
4 |
|a 615.19
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100 |
1 |
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|a Agarwal, Shikha,
|e author.
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245 |
1 |
0 |
|a Imidazole-based drug discovery /
|c Shikha Agarwal.
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264 |
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1 |
|a Amsterdam, Netherlands ;
|a Oxford, United Kingdom ;
|a Cambridge, MA, United States :
|b Elsevier,
|c [2022]
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264 |
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4 |
|c �2022
|
300 |
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|a 1 online resource (xix, 351 pages) :
|b illustrations.
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336 |
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|a text
|b txt
|2 rdacontent
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337 |
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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490 |
1 |
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|a Heterocyclic drug discovery series
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504 |
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|a Includes bibliographical references and index.
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505 |
8 |
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|6 880-01
|a 2.3.5 Using benzil, aldehyde, and ammonium acetate -- 2.4 Tetra-substituted imidazole derivatives -- 2.4.1 Using aminoethylpiperazine -- 2.4.2 Using prop-2-ynylamine -- 2.4.3 Using benzil, aldehydes, ammonium acetate, and aniline -- 3 Imidazole hybrids -- 3.1 Imidazole fused heterocycles -- 3.2 Benzimidazole fused heterocycles -- 4 Benzimidazole -- 4.1 Hoebrecker synthesis -- 4.2 Synthesis of benzimidazoles using o -phenylenediamine and acids -- 4.3 Synthesis of benzimidazoles using o -phenylenediamine and acid anhydride -- 4.4 Synthesis of benzimidazoles using o -phenylenediamine and alcohols
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505 |
8 |
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|a 4.5 Synthesis of benzimidazoles using o -phenylenediamine and alkyl halides -- 4.6 Synthesis of benzimidazoles using ketones -- 4.7 Synthesis of benzimidazoles using o -phenylenediamine and aldehydes -- 5 Conclusion -- Conflict of interest -- Acknowledgments -- Funding source -- References -- Chapter 2 Biological profile of imidazole-based compounds as anticancer agents -- 1 Introduction -- 2 Imidazole-based heterocycles -- 2.1 Imidazole as the main nucleus in the anticancer compounds -- 2.1.1 Mono-substituted imidazole derivatives -- 2.1.2 Disubstituted imidazole derivatives
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505 |
8 |
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|a 2.1.3 Trisubstituted imidazole derivatives -- 2.1.4 Tetra-substituted imidazole derivatives -- 2.2 Imidazole hybrids as anticancer agents -- 2.3 Imidazole fused heterocycles -- 2.3.1 Imidazole fused heterocycles -- 2.3.2 Benzimidazole fused heterocycles -- 2.4 Imidazole-based metal complexes as anticancer agents -- 3 Conclusion and future challenges -- Conflict of interest -- Acknowledgment -- Funding source -- References -- Chapter 3 Recent advancements on imidazole containing heterocycles as antitubercular agents -- 1 Introduction -- 2 Imidazole-based heterocycles -- 2.1 Substituted imidazoles
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505 |
8 |
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|a 2.2 Hybrid Imidazoles -- 2.3 Fused imidazoles -- 2.4 Linker imidazole -- 2.5 Benzimidazole -- 3 Conclusion -- Conflict of interest -- Acknowledgments -- Funding source -- References -- Chapter 4 Imidazole derivatives: Impact and prospects in antiviral drug discovery -- 1 Introduction -- 2 Imidazole derivatives and their action against different viruses -- 2.1 Zika virus -- 2.2 Influenza -- 2.3 SARS-COVID -- 2.4 Dengue -- 2.5 Hepatitis -- 2.6 HIV -- 2.7 Miscellaneous -- 3 Conclusion -- Acknowledgments -- Conflict of interest -- Funding source -- References
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|a Chapter 5 Imidazole heterocycles: Therapeutically potent lead compounds as antimicrobials.
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588 |
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|a Online resource; title from PDF title page (ScienceDirect platform, viewed April 19, 2022).
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650 |
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0 |
|a Imidazoles.
|
650 |
|
0 |
|a Drugs.
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650 |
|
0 |
|a Drug development.
|
650 |
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2 |
|a Imidazoles
|0 (DNLM)D007093
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|
2 |
|a Pharmaceutical Preparations
|0 (DNLM)D004364
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650 |
|
6 |
|a Imidazole.
|0 (CaQQLa)201-0026559
|
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|
6 |
|a M�edicaments.
|0 (CaQQLa)201-0002990
|
650 |
|
6 |
|a M�edicaments
|x D�eveloppement.
|0 (CaQQLa)201-0306620
|
650 |
|
7 |
|a Drug development
|2 fast
|0 (OCoLC)fst00898670
|
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|
7 |
|a Drugs
|2 fast
|0 (OCoLC)fst00898761
|
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|
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|a Imidazoles
|2 fast
|0 (OCoLC)fst01715755
|
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0 |
8 |
|i Print version:
|z 0323854796
|w (OCoLC)1257403690
|
830 |
|
0 |
|a Heterocyclic drug discovery.
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780323854795
|z Texto completo
|
880 |
0 |
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|6 505-01/(S
|a Intro -- Imidazole-Based Drug Discovery -- Copyright -- Dedication -- Contents -- Contributors -- About the authors -- Preface -- Acknowledgments -- Chapter 1 Imidazole and its derivatives: Introduction and synthetic aspects -- 1 Introduction -- 2 Synthesis of substituted imidazoles -- 2.1 Mono-substituted imidazole derivatives -- 2.2 Di-substituted imidazole derivatives -- 2.3 Tri-substituted imidazole derivatives -- 2.3.1 Using 2,3-diaminomaleonitrile -- 2.3.2 Using the Van Leusen method -- 2.3.3 Using 2,3-dioxo-3-substituted propanoates -- 2.3.4 Using α -aminoketones
|