Advanced drug delivery systems in the management of cancer /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dua, Kamal
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2021.
Temas:
Drug delivery systems.
Cancer > Chemotherapy.
Drug Delivery Systems > methods
Drug Delivery Systems
Syst�emes d'administration de m�edicaments.
Cancer > Chimioth�erapie.
Cancer > Chemotherapy
Drug delivery systems
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Advanced Drug Delivery Systems in the Managementof Cancer
  • Copyright
  • Dedication
  • Contents
  • Contributors
  • Editor biographies
  • Chapter 1 Introduction to cancer cell biology
  • 1 Introduction
  • 2 Types of cancer
  • 3 Pathophysiology of cancer
  • 3.1 Sustained multiplication (proliferative) signaling
  • 3.2 Shunning of anti-growth signals
  • 3.3 Avoidance of immune annihilation (destruction)
  • 3.4 Avoidance of apoptosis
  • 3.5 Tissue invasion and metastasis
  • 3.6 Extended (sustained) tumor angiogenesis
  • 3.7 Endless multiplication (replication) potential
  • 3.8 Deregulation of cell energetics
  • 3.9 Oncogenes and tumor suppressor genes
  • 3.10 Breast cancer biology
  • 3.11 Gastric cancer biology
  • 3.12 Pancreatic cancer biology
  • 3.13 Lung cancer biology
  • 3.14 Leukemia biology
  • References
  • Chapter 2 Current practice in cancer pharmacotherapy
  • 1 Introduction
  • 1.1 Lung
  • 1.2 Breast (female)
  • 1.3 Prostate
  • 1.4 Colon
  • 1.5 Skin
  • 2 Conclusions
  • References
  • Chapter 3 Current practices in oncology drug delivery
  • 1 Introduction
  • 1.1 Historical background
  • 1.2 Ancient theories about cancer
  • 1.3 Description and epidemiology of cancer
  • 2 Past therapeutic approaches in cancer (1900 and earlier)
  • 3 Current approaches of drug delivery
  • 3.1 Targeted therapy in cancer
  • 3.1.1 Molecular targeted therapy
  • 3.1.2 Monoclonal antibodies
  • 3.1.3 Immunotoxins
  • 3.2 Gene therapy
  • 3.2.1 Gene therapy in clinics
  • 3.3 Bacterial-mediated therapy
  • 3.4 Nanomedicine
  • 3.5 Immune checkpoint inhibitors
  • 3.6 Radiomics and pathomics
  • 3.6.1 Combining radiomics and pathomics with genomics
  • 3.6.2 Combining radiomics and pathomics with artificial intelligence
  • 3.6.3 Combining radiomics and pathomics with tumor markers
  • 3.6.4 Combining radiomics with pathomics immunological detection
  • 3.7 Theranostics
  • 4 Future directions
  • References
  • Chapter 4 Emerging need of advanced drug delivery systems in cancer
  • 1 Introduction
  • 2 Multidrug resistance in cancer cells
  • 3 Toxic effects of chemotherapy
  • 4 Hazardous effects of radiation oncology
  • 5 Polypharmacology in anticancer therapy
  • 6 Advanced drug delivery systems
  • 7 Stimuli-responsive drug delivery systems
  • 7.1 pH-responsive
  • 7.2 Light-responsive
  • 7.3 Redox-responsive
  • 7.4 Enzyme-responsive
  • 8 Conclusion and future perspectives
  • References
  • Chapter 5 Target drug delivery in cancer
  • 1 Introduction
  • 2 Ligand-mediated targeting (surface modification)
  • 2.1 Peptide as targeting ligand
  • 2.2 Aptamer-mediated drug targeting
  • 2.3 Small molecule-mediated targeted drug delivery
  • 2.3.1 Folate receptor targeting
  • 2.3.2 Anisamide-mediated targeting
  • 2.3.3 Sugar-mediated targeting
  • 3 Protein-mediated targeting
  • 3.1 Antibody-mediated targeting
  • 3.2 Transferrin-mediated targeting
  • 3.3 Lectin-mediated drug delivery

Ejemplares similares