Reciprocal translation between pathophysiology and practice in health and disease /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Soeters, Peter B. (Autor), Leeuw, Peter de (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2021.
Temas:
Physiology, Pathological.
Medicine > Practice.
Electronic books.
Physiopathologie.
M�edecine > Pratique.
Livres num�eriques.
e-books.
Medicine > Practice
Physiology, Pathological
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Reciprocal Translation Between Pathophysiology and Practice in Health and Disease
  • Copyright
  • Contents
  • Part I: Pathophysiological mechanisms in disease
  • Chapter 1: Reciprocal translation between pathophysiology and practice in health and disease
  • Chapter 2 : General principles of the repair mechanism
  • Introduction
  • The inflammatory response
  • The ``proinflammatory phase��
  • The ``antiinflammatory phase��
  • Formation of building blocks for repair
  • Pathophysiological effects after trauma (Table 1)
  • Evolutionary aspects
  • Conclusion
  • References
  • Chapter 3: Cardiovascular responses to injury
  • Introduction
  • Mechanisms of the local vascular response
  • Role of the local renin-angiotensin system
  • Role of local adrenergic mechanisms
  • Regional ischemia-related vascular responses
  • Role of the autonomic nervous system
  • Glucosensitive efferent adrenergic mechanisms
  • Thermosensitive efferent adrenergic mechanisms
  • Barosensitive efferent adrenergic mechanisms
  • Systemic vascular responses to injury
  • Role of the kidney
  • Conclusions
  • References
  • Chapter 4: Insulin resistance as an adaptive mechanism
  • Introduction
  • Insulin resistance and intermediary metabolism
  • Insulin resistance in pure starvation
  • Insulin resistance in stress starvation (Fig. 1)
  • Insulin resistance in pregnancy and growth
  • Insulin resistance and the response to injury
  • The possible evolutionary benefit of insulin resistance
  • Insulin resistance and survival
  • The downside of insulin resistance: The metabolic syndrome
  • Conclusion
  • References
  • Chapter 5: Hypercholesterolemia, harm, or benefit?
  • Introduction
  • Metabolism and transport of cholesterol
  • Functions of cholesterol
  • Cholesterol during infections and inflammation
  • Cholesterol in states of growth
  • Cholesterol and cardiovascular disease
  • Conclusion
  • References
  • Chapter 6: Macronutrient metabolism in starvation and stress
  • Introduction
  • Protein metabolism in starvation and stress
  • Changes in amino acid metabolism as a consequence of stress (Figs. 3 and 4)
  • Glutamine metabolism during host response and growth
  • Pathophysiology and role of the most studied single amino acids in clinical practice (glutamine and arginine)
  • Glutamine
  • The significance of glutamine concentrations and fluxes
  • Is there a glutamine shortage in disease and trauma?
  • The significance of arginine in conditions of stress
  • Does arginine deficiency exist?
  • Synthesis of arginine
  • Asymmetric dimethyl-arginine
  • Nutritional and metabolic consequences
  • Conclusions
  • References
  • Chapter 7: The role of ectopic adipose tissue: Benefit or deleterious overflow?
  • Introduction
  • Does overflow of fat exist?
  • The beneficial role of inflammation and insulin resistance (for details see Chapter 4)
  • Epicardial adipose tissue (see Fig. 1)
  • Perinodal adipose tissue

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