The exposome : a new paradigm for the environment and health /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Miller, Gary W. (Professor of environmental health) (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, United Kingdom ; San Diego, CA, United States ; Cambridge, MA, United States ; Kidlington, Oxford, United Kingdom : Academic Press, an Imprint of Elsevier, [2020]
Edición:Second edition.
Temas:
Environmentally induced diseases.
Genomes.
Environmental Exposure > adverse effects
Genome
Maladies de l'environnement.
G�enomes.
Environmentally induced diseases
Genomes
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • The Exposome
  • Copyright Page
  • Dedication
  • Contents
  • Biography
  • Preface to the second edition
  • Preface to the first edition
  • 1. The exposome: purpose, definitions, and scope
  • 1.1 Introduction
  • 1.2 What is the exposome?
  • 1.3 What is a paradigm?
  • 1.4 What is the environment?
  • 1.5 What is health?
  • 1.6 Balkanization of the exposome
  • 1.7 Darwin would be proud
  • 1.8 If it is so obvious, why this book?
  • 1.9 The exposome community
  • 1.10 Tomayto, tomahto
  • apoptosis, a-POP-tosis
  • exposome, Xposome
  • 1.11 Teaching/learning the exposome
  • 1.12 Obstacles and opportunities
  • 1.13 Discussion questions
  • References
  • Further reading
  • 2. Genes, genomes, and genomics: advances and limitations
  • 2.1 DNA, no longer a secret
  • 2.2 The Human Genome Project: DNA at scale
  • 2.3 Heritability
  • 2.4 The gene versus environment continuum
  • 2.4.1 A dangerous metaphor?
  • 2.5 Large-scale genetics
  • 2.6 Epigenetics: a clear gene-environment interface
  • 2.7 Using genetic know-how to better understand environmental influences
  • 2.8 Obstacles and opportunities
  • 2.9 Discussion questions
  • References
  • Further reading
  • 3. Nurturing science
  • 3.1 Introducing nurture
  • 3.2 Nutrition: feeding our exposome
  • 3.3 Too much of a good thing
  • 3.4 Dietary insight from the laboratory
  • 3.5 Physical activity-exercising your exposome
  • 3.6 Psychosocial interactions and cognitive development: your humanity and the exposome
  • 3.7 What actions can the Example family take to improve their exposome?
  • 3.8 Immunity and the exposome
  • 3.9 Nurture and evolution
  • 3.10 Evaluating nurture
  • 3.11 Tick-tock, tick-tock. Is that my epigenetic clock?
  • 3.12 Obstacles and opportunities
  • 3.13 Discussion questions
  • 5.5 Proteome
  • 5.6 Pharmacogenomics/toxicogenomics
  • 5.7 Epigenomics
  • 5.8 Metabolome
  • 5.9 What to do with all of these -omes
  • 5.10 The exposome and exposomics
  • 5.11 Obstacles and opportunities
  • 5.12 Discussion questions
  • References
  • Further reading
  • 6. Innovation and the exposome
  • 6.1 Introduction
  • 6.2 A pile of something
  • 6.3 Moonshots and missed shots
  • 6.4 Great by association
  • 6.5 Acceptable failure, intolerable incompetence
  • 6.6 A brief history of time (of flight) and other technologies
  • 6.7 Measuring the previously unmeasurable
  • 6.8 The science of innovation

Ejemplares similares