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|2 23
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| 245 |
0 |
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|a Systemic lupus erythematosus :
|b basic, applied and clinical aspects /
|c edited by George C. Tsokos.
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| 250 |
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|a Second edition
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| 264 |
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1 |
|a London :
|b Academic Press, an imprint of Elsevier,
|c [2020]
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| 264 |
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4 |
|c �2020
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| 300 |
|
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|a 1 online resource (xxix, 652 pages) :
|b color illustrations
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| 336 |
|
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 504 |
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|a Includes bibliographical references.
|
| 506 |
1 |
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|a Legal Deposit;
|c Only available on premises controlled by the deposit library and to one user at any one time;
|e The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
|5 WlAbNL
|
| 540 |
|
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|a Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.
|5 WlAbNL
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| 505 |
0 |
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|a Cover -- Title -- Copyright -- Dedication -- Contents -- Contributors -- Introduction -- Introduction to the second edition -- Part I -- Epidemiology and diagnosis -- Chapter 1 -- History of systemic lupus erythematosus with an emphasis on certain recent major issues -- History of clinical observations -- The age of dermatology -- Transition of lupus erythematosus to systemic lupus erythematosus -- History of laboratory investigations -- Development of clinical tests -- History of genetics of SLE -- History of therapy in SLE with an emphasis on the use of steroids
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| 505 |
8 |
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|a History of classification criteria for SLE -- References -- Chapter 2 -- The patient -- Improve the interactions with your patients -- Do not make your patient wait -- Smile as you enter the patient's room -- Make a visible show of hand washing -- Shake hands -- Acknowledge and greet others in the room -- Ask open-ended questions -- Provide a mechanism for your patient to set the agenda -- Speak in nonmedical terms -- Be honest -- Learn to be empathetic -- Always examine your patient -- End the visit with, "Do you have any other concerns or questions?" -- Consulting in the hospital
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| 505 |
8 |
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|a Improving adherence -- Disability -- Patient education -- The lupus secrets -- References -- Chapter 3 -- A plea of a young patient to the lupus experts -- Reference -- Chapter 4 -- Epidemiology -- Introduction -- Incidence and prevalence -- Distribution according to gender -- Distribution according to age -- Distribution according to ethnic/racial group -- Distribution around the world -- Factors that affect the course of SLE -- Impact of race/ethnicity -- Impact of gender -- Mortality and survival in SLE -- References -- Chapter 5 -- Measuring disease activity -- References
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| 505 |
8 |
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|a Chapter 6 -- Disease development and outcome -- Historical perspective -- Clinical manifestations -- Assessment of disease activity -- Disease damage -- Patient reported outcomes -- Mortality -- Causes of death -- Treatment guidelines and quality indicators -- Conclusions -- References -- Chapter 7 -- Socioeconomic aspects of SLE -- Introduction -- Sociodemographic determinants of health in SLE -- Gender as a construct in risk and morbidity -- Race/ethnicity as a multidimensional determinant of outcomes -- Age and aging -- Income, poverty, and educational attainment
|
| 650 |
|
0 |
|a Systemic lupus erythematosus.
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| 650 |
|
0 |
|a Biochemical markers.
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| 650 |
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0 |
|a Comorbidity.
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| 650 |
1 |
2 |
|a Lupus Erythematosus, Systemic
|x diagnosis
|0 (DNLM)D008180Q000175
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| 650 |
2 |
2 |
|a Lupus Erythematosus, Systemic
|x physiopathology
|0 (DNLM)D008180Q000503
|
| 650 |
2 |
2 |
|a Lupus Erythematosus, Systemic
|x therapy
|0 (DNLM)D008180Q000628
|
| 650 |
|
2 |
|a Lupus Erythematosus, Systemic
|0 (DNLM)D008180
|
| 650 |
2 |
2 |
|a Biomarkers
|0 (DNLM)D015415
|
| 650 |
2 |
2 |
|a Comorbidity
|0 (DNLM)D015897
|
| 650 |
|
6 |
|a Lupus �eryth�emateux diss�emin�e.
|0 (CaQQLa)201-0250523
|
| 650 |
|
6 |
|a Marqueurs biologiques.
|0 (CaQQLa)201-0177920
|
| 650 |
|
6 |
|a Comorbidit�e.
|0 (CaQQLa)201-0319011
|
| 650 |
|
7 |
|a Comorbidity
|2 fast
|0 (OCoLC)fst00871254
|
| 650 |
|
7 |
|a Biochemical markers
|2 fast
|0 (OCoLC)fst00831950
|
| 650 |
|
7 |
|a Systemic lupus erythematosus
|2 fast
|0 (OCoLC)fst01141443
|
| 655 |
|
4 |
|a Internet Resources.
|
| 700 |
1 |
|
|a Tsokos, George C.,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Systemic lupus erythematosus.
|d London : Academic Press/Elsevier, [2020]
|z 9780128145517
|w (OCoLC)1122448772
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128145517
|z Texto completo
|
| 880 |
0 |
|
|6 505-00/(S
|a Introduction to the second edition -- History of systemic lupus erythematosus with an emphasis on certain recent major issues -- The patient -- A plea of a young patient to the lupus experts -- Epidemiology -- Measuring disease activity -- Disease development and outcome -- Socioeconomic aspects of SLE -- Biomarkers in systemic lupus erythematosus -- Overview of the pathogenesis of systemic lupus erythematosus -- System lupus erythematosus and the environment -- Genes and genetics in human SLE -- Monogenic lupus -- Hormones -- Clinical aspects of the complement system in systemic lupus erythematosus -- T cells -- B cells in SLE -- Neutrophils in systemic lupus erythematosus -- The role of dendritic cells in systemic lupus erythematosus -- Cytokines -- RNA/DNA sensing in SLE--Toll-like receptors and beyond -- The role of interferons in systemic lupus erythematosus -- Fcγ receptors in autoimmunity and end-organ damage -- Apoptosis, autophagy, and necrosis -- Infections in early systemic lupus erythematosus pathogenesis -- Microbiota influences on systemic lupus erythematosus and S�jgren's syndrome -- Origin of autoantibodies -- Anti-DNA antibodies -- Antihistone and antispliceosome antibodies -- Immune complexes in systemic lupus erythematosus -- MicroRNA in systemic lupus erythematosus -- Metabolic control of lupus pathogenesis: central role for activation of the mechanistic target of rapamycin -- Epigenetics -- What do mouse models teach us about human SLE? -- Genes and genetics of murine systemic lupus erythematosus -- Mechanisms of renal damage in systemic lupus erythematosus -- Mechanisms of vascular damage in systemic lupus erythematosus -- The mechanism of skin damage -- Pathogenesis of tissue injury in the brain in patients with systemic lupus erythematosus -- Constitutional symptoms and fatigue in systemic lupus erythematosus -- The musculoskeletal system in SLE -- Cutaneous lupus erythematosus -- The clinical evaluation of kidney disease in systemic lupus erythematosus -- The pathology of lupus nephritis -- Cardiovascular disease in systemic lupus erythematosus: an update -- The lung in systemic lupus erythematosus -- Gastrointestinal, hepatic, and pancreatic disorders in systemic lupus erythematosus -- Systemic lupus erythematosus and infections -- Malignancies in systemic lupus erythematosus -- The nervous system in systemic lupus erythematosus -- Overlap syndromes -- Systemic lupus erythematosus and the eye -- Fertility and pregnancy in systemic lupus erythematosus -- Neonatal lupus: Clinical spectrum, biomarkers, pathogenesis, and approach to treatment -- Incomplete lupus syndromes -- Lupus in children -- Drug-induced lupus -- Vasculitis in lupus -- Pathogenesis of antiphospholipid syndrome -- Antibodies and diagnostic tests in antiphosholipid syndrome -- Clinical manifestations -- Nonsteroidal antiinflammatory drugs in systemic lupus erythematosus -- Value of antimalarial drugs in the treatment of lupus -- Systemic glucocorticoids -- Cytotoxic drug treatment -- Treatment of antiphospholipid syndrome -- New treatments of systemic lupus erythematosus -- Repositioning drugs for systemic lupus erythematosus.
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