A pharmacology primer : techniques for more effective and strategic drug discovery /

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A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensa...

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Bibliographic Details
Call Number:Libro Electrónico
Main Author: Kenakin, Terrence P. (Author)
Format: Electronic eBook
Language:Inglés
Published: London, United Kingdom ; San Diego, CA : Academic Press, an imprint of Elsevier, [2019]
Edition:Fifth edition.
Subjects:
Pharmacology, Experimental.
Drugs > Dose-response relationship.
Receptors, Drug > physiology
Dose-Response Relationship, Drug
Pharmacology > methods
Pharmacologie exp�erimentale.
M�edicaments > Relations dose-effet.
MEDICAL > Pharmacology.
Drugs > Dose-response relationship
Pharmacology, Experimental
Online Access:Texto completo
Table of Contents:
  • What is pharmacology?
  • How different tissues process drug response
  • Drug-receptor theory
  • Pharmacological assay formats : binding
  • Agonists : the measurement of affinity and efficacy in functional assays
  • Orthosteric drug antagonism
  • Allosteric modulation
  • The optimal design of pharmacological experiments
  • Pharmacokinetics
  • Safety pharmacology
  • The drug discovery process
  • Statistics and experimental design
  • Selected pharmacological methods
  • Exercises in pharmacodynamics and pharmacokinetics.

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