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The cellular secretome and organ crosstalk /
The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included....
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London ; San Diego, CA :
Academic Press,
[2018]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 020 | |a 9780128097199 |q (electronic bk.) | ||
| 020 | |a 0128097191 |q (electronic bk.) | ||
| 020 | |z 9780128095188 | ||
| 020 | |z 0128095180 | ||
| 035 | |a (OCoLC)1040694315 |z (OCoLC)1041525696 |z (OCoLC)1041879064 |z (OCoLC)1235842406 | ||
| 050 | 4 | |a QH583 | |
| 060 | 4 | |a 2018 H-172 | |
| 060 | 4 | |a QU 375 | |
| 072 | 7 | |a SCI |x 056000 |2 bisacsh | |
| 082 | 0 | 4 | |a 571.6 |2 23 |
| 100 | 1 | |a Eckel, Juergen. | |
| 245 | 1 | 4 | |a The cellular secretome and organ crosstalk / |c Juergen Eckel. |
| 264 | 1 | |a London ; |a San Diego, CA : |b Academic Press, |c [2018] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development. Summarizes our current knowledge on the secretome of different cells and tissues. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed June 19, 2018). | |
| 505 | 0 | |a 1. General Introduction 2. Adipose tissue -- a major secretory organ 3. Skeletal muscle -- a novel secretory organ 4. Adipomyokines -- an extended view on the crosstalk scenario 5. Secretory malfunction -- a key step to metabolic diseases 6. Technical Annex: Secretome and crosstalk analysis | |
| 650 | 0 | |a Cytology. | |
| 650 | 0 | |a Metabolism |x Regulation. | |
| 650 | 0 | |a Cell interaction. | |
| 650 | 0 | |a Biological transport. | |
| 650 | 1 | 2 | |a Cell Communication |0 (DNLM)D002450 |
| 650 | 2 | 2 | |a Adipose Tissue |x metabolism |0 (DNLM)D000273Q000378 |
| 650 | 2 | 2 | |a Biological Transport |0 (DNLM)D001692 |
| 650 | 2 | 2 | |a Muscle, Skeletal |x metabolism |0 (DNLM)D018482Q000378 |
| 650 | 2 | 2 | |a Receptor Cross-Talk |0 (DNLM)D020239 |
| 650 | 2 | |a Cell Biology |0 (DNLM)D003585 | |
| 650 | 2 | |a Cytology |0 (DNLM)D000093222 | |
| 650 | 6 | |a Cytologie. |0 (CaQQLa)201-0040099 | |
| 650 | 6 | |a M�etabolisme |x R�egulation. |0 (CaQQLa)201-0043156 | |
| 650 | 6 | |a Cellules |x Interaction. |0 (CaQQLa)201-0005047 | |
| 650 | 6 | |a Transport biologique. |0 (CaQQLa)201-0011115 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Cell interaction |2 fast |0 (OCoLC)fst00850189 | |
| 650 | 7 | |a Biological transport |2 fast |0 (OCoLC)fst00832345 | |
| 650 | 7 | |a Cytology |2 fast |0 (OCoLC)fst00886282 | |
| 650 | 7 | |a Metabolism |x Regulation |2 fast |0 (OCoLC)fst01017486 | |
| 655 | 4 | |a Internet Resources. | |
| 776 | 0 | 8 | |i Print version: |z 9780128095188 |z 0128095180 |w (OCoLC)1002834443 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128095188 |z Texto completo |
| 880 | 0 | |6 505-00/(S |a Front Cover; The Cellular Secretome and Organ Crosstalk; The Cellular Secretome and Organ Crosstalk; Copyright; Contents; About the Author; 1 -- General Introduction; REFERENCES; 2 -- Adipose Tissue: A Major Secretory Organ; MECHANISMS OF ADIPOKINE RELEASE; CLASSICAL OR ENDOPASMIC RETICULUM/GOLGI-DEPENDENT PATHWAYS; ADIPONECTIN; LEPTIN; NONCLASSICAL PROTEIN SECRETION; TRANSPORTER-MEDIATED EXPORT OF FGF2; SHEDDING OF TNFα AND DPP4; MULTIPLE EXPORT ROUTES OF IL-1β; Auto- and Paracrine Crosstalk Within Adipose Tissue and the Regulation of Adipogenesis; ADIPONECTIN AND LEPTIN | |
| 880 | 8 | |6 505-00/(S |a RETINOL-BINDING PROTEIN 4HEME OXYGENASE-1; WNT1-INDUCIBLE SIGNALING PATHWAY PROTEIN 2; SECRETED FRIZZLED-RELATED PROTEINS; CHEMERIN; Adipose Tissue and Its Endocrine Function; THE FAT-MUSCLE CROSSTALK; TNFα AND IL-6; MCP-1 AND VASPIN; ADIPONECTIN AND LEPTIN; DPP4 AND VISFATIN IMPACT ON SKELETAL MUSCLE; THE FAT-LIVER CROSSTALK; THE FAT-PANCREAS CROSSTALK; Impact on α-Cells; Impact on β-Cells; ADIPONECTIN AND LEPTIN: ANTAGONIST EFFECTS ON PANCREATIC β-CELLS; DPP4 AND VISFATIN: POTENTIAL MEDIATORS OF β-CELL DYSFUNCTION; The Adipovascular Axis | |