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Nanoscale fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology /

Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: th...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Grumezescu, Alexandru Mihai (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Kidlington, Oxford : William Andrew, an imprint of Elsevier, [2018]
Colección:Pharmaceutical nanotechnology series.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Nanoscale fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology /  |c edited by Alexan Mihai Grumezescu. 
264 1 |a Kidlington, Oxford :  |b William Andrew, an imprint of Elsevier,  |c [2018] 
264 4 |c �2018 
300 |a 1 online resource :  |b illustrations 
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337 |a computer  |b c  |2 rdamedia 
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490 1 |a Pharmaceutical nanotechnology series 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (EBSCO, viewed December, 08, 2017). 
520 |a Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: the need for less toxic reagents, simplification of the procedure to allow economic scale-up, and optimization to improve yield and entrapment efficiency. Written by a diverse range of international researchers, the chapters examine characterization and manufacturing of nanomaterials for pharmaceutical applications. Regulatory and policy aspects are also discussed. This book is a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about how nanomaterials can best be utilized. 
505 0 |a 1. Fabrication of polymeric core-shell nanostructures -- 2. Emulsification-diffusion method to obtain polymeric nanoparticles: two decades of research -- 3. Tools and Techniques for the optimized synthesis, reproducibility and scale up of desired nanostructures from plant derived material and their role in pharmaceutical properties -- 4. Scale up of biopharmaceuticals production -- 5. Physicochemical and morphological characterization of pharmaceutical nanocarriers and mathematical modelling of drug encapsulation/release mass transfer processes -- 6. Biopharmaceutics and pharmacokinetics of multifunctional nanoparticles -- 7. Technological delivery systems to improve biopharmaceutical properties -- 8. From physicochemically stable nanocarriers to targeted drug delivery: in-vivo pharmacokinetic, pharmacodynamic and biodistribution studies -- 9. Sterile dosage forms loaded nanosystems for parenteral, nasal, pulmonary and ocular administration -- 10. Quantitative Characterization of Targeted Nanoparticulate Formulations for Prediction of Clinical Efficacy -- 11. Analytical tools for reliable in vitro and in vivo performance testing of drug nanocrystals -- 12. Application of one-step affinity purification of drug-binding proteins with practical magnetic nanoparticles to drug discovery -- 13. Molecularly Imprinted Polymers as Separation Tools -- 14. Detection of DNA damage induced by nanomaterials -- 15. Pharmacological usage of an enzyme inhibitor -- a selective inhibitor of 3-mercaptopyruvate sulfurtransferase reaction intermediate to control generation of polysulfide -- 16. Regulatory Consideration in Nanotechnology Based Drug Products. 
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