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Immunity and inflammation in health and disease : emerging roles of nutraceuticals and functional foods in immune support /
Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which our immune system works, the signals that trigger immune response and how foods can be used to contain inflam...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
[2017]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Immunity and Inflammation in Health and Disease; Copyright Page; Dedication; Contents; List of Contributors; Preface; I. Innate and Adaptive Immune Systems: Components and Regulation; 1 Innate and Adaptive Immunity: Barriers and Receptor-Based Recognition; 1.1 Introduction; 1.2 The Components of the Immune Response (External and Internal Elements); 1.3 The Innate Immune System (Cell Types, Signaling); 1.4 Inflammation and Innate Immunity; 1.5 Induction of Adaptive Immunity (Antigen Presentation as a Key Event); 1.6 Cell Types in the Adaptive Immune Response.
- 1.7 Crosstalk Between the Innate and Adaptive Immune Responses1.8 The Vascular Endothelium as a Converging Site for Both Innate and Adaptive Immunity; 1.9 Chronic Diseases of the Innate and Adaptive Immune Systems; 1.10 Improving Immunity for Prevention and Care; 1.11 Summary; References; 2 Innate Immunity at Birth: Implications for Inflammation and Infection in Newborns; 2.1 Introduction; 2.2 Microbiome in Shaping the Newborn Immune System; 2.3 Mucosal Immunity at Birth; 2.4 The Innate Immune Cells of the Newborn; 2.4.1 Neonatal Neutrophils; 2.4.2 Neonatal Monocytes.
- 2.4.3 Neonatal Macrophages2.4.4 Neonatal Dendritic Cells; 2.4.5 Neonatal Natural Killer (NK) Cells; 2.5 Soluble Plasma Components; 2.6 Conclusion; References; 3 Redox Signaling and the Onset of the Inflammatory Cascade; 3.1 Introduction; 3.2 ROS Generation During the Onset of the Inflammatory Cascade; 3.3 Redox Control of Inflammatory Mediators; 3.4 Redox Control of Antioxidant and Anti-inflammatory Transcription Factors; 3.5 Emerging Role of Peroxiredoxins in the Onset of the Inflammatory Cascade; 3.6 Conclusions and Perspectives; References.
- II. Reactive Oxygen Species, Oxidative Stress and Immune Cell Activation4 Reactive Oxygen Species, Oxidative Damage and Cell Death; 4.1 Introduction; 4.2 Endogenous ROS Production; 4.3 Exogenous ROS Production; 4.4 Physiological Role of Reactive Oxygen Species; 4.5 Oxidative Stress; 4.6 Oxidative Damage is Outcome of Oxidative Stress; 4.7 Cell Death; 4.8 Conclusions; References; 5 Mitochondrial ROS and T Cell Activation; 5.1 Introduction; 5.2 Reactive Oxygen Species; 5.3 Sources of Mitochondrial ROS; 5.4 Regulation of mROS; 5.5 Targets of mROS; 5.6 Mitochondrial ROS in T Cell Activation.
- 5.7 SummaryReferences; 6 Overcoming Oxidants and Inflammation: Endothelial Targeting of Antioxidants to Combat Chronic Inflammatory Disease; 6.1 Introduction; 6.2 Inflammation and Disease; 6.2.1 Vascular Endothelium, Reactive Species, and Inflammatory Agents; 6.2.2 Markers of Oxidative Stress and Inflammation; 6.3 Antioxidants as therapeutics; 6.4 Antioxidant Targeting Strategies; 6.5 Nanocarrier-Mediated Delivery of Antioxidants; 6.5.1 Liposomes; 6.5.2 Polymer Nanocarriers; 6.5.3 Magnetic Nanoparticles; 6.5.4 Lipid Nanoparticles and Complexes; 6.6 Conclusions; References.