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Genome stability : from virus to human application /

Genome Stability: From Virus to Human Application covers the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, with the latter including major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associa...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Kovalchuk, Igor (Editor ), Kovalchuk, Olga (Physician) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, United Kingdom : Academic Press is an imprint of Elsevier, 2016.
Colección:Translational epigenetics series.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Genome Stability; Translational Epigenetics Series; Genome Stability: From Virus to Human Application; Copyright; Contents; List of Contributors; Introduction; 1
  • Genome Stability: An Evolutionary Perspective ; 1. INTRODUCTION; 2. EVOLUTION THEORIES AND MY REFLECTION ON THEM; 3. THE ROLE OF SYMBIOSIS IN GENOME EVOLUTION; 3.1 Changes in the Structure of the Organellar Genome Over Time; 3.2 Mutation Rates in Organellar Genomes and Adaptive Evolution; 3.3 Symbiotic Interactions Between Viruses, Prokaryotes, and Eukaryotes: The Role of Transposable Elements
  • 5. THE VIRAL POLYMERASE AS A SOURCE OF ERROR6. OTHER VIRAL DETERMINANTS OF MUTATION RATE; 7. RECOMBINATION; 8. THE EFFECT OF REPLICATION MODE ON MUTATION FREQUENCY; 9. THE EFFECT OF CELLULAR FACTORS ON VIRUS MUTATION RATE; 10. MECHANISMS UNDERLYING GENETIC ROBUSTNESS IN RNA VIRUSES; 11. RNA VIRUSES ON THE EDGE; 12. VIRUS GENETIC VARIABILITY AND THE VIRUS-HOST "ARMS RACE"; 13. TAKING ADVANTAGE OF THE MUTABILITY OF RNA VIRUSES; 14. CONCLUSION; GLOSSARY; LIST OF ABBREVIATIONS; REFERENCES; 3
  • Genome Instability in DNA Viruses ; 1. OVERVIEW