Cargando…

Gene-environment interactions in psychiatry : nature, nurture, neuroscience /

Gene-Environment Interactions in Psychiatry: Nature, Nurture, Neuroscience begins with the basic aspects of gene-environment studies, such as basic genetics, principles of animals modeling, and the basic processes of how environmental factors affect brain and behavior, with part two describing the m...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Ellenbroek, B. A. (Bart A.), 1958-
Otros Autores: Youn, Jiun
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, �2016.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000Ma 4500
001 SCIDIR_ocn955142121
003 OCoLC
005 20231120112126.0
006 m o d
007 cr |n|||||||||
008 160805s2016 enk o 001 0 eng d
040 |a IDEBK  |b eng  |e pn  |c IDEBK  |d OPELS  |d EBLCP  |d OCLCQ  |d N$T  |d VLB  |d UPM  |d OCLCQ  |d U3W  |d KIJ  |d OCLCQ  |d D6H  |d OCLCF  |d ABC  |d NLE  |d YDX  |d WYU  |d OCLCQ  |d UKMGB  |d OCLCO  |d OCLCQ  |d OCLCO 
015 |a GBB6B0684  |2 bnb 
016 7 |a 017969415  |2 Uk 
019 |a 960737130  |a 1007770486  |a 1066647722  |a 1378334734 
020 |a 012801783X  |q (electronic bk.) 
020 |a 9780128017838  |q (electronic bk.) 
020 |z 9780128016572 
020 |z 0128016574 
035 |a (OCoLC)955142121  |z (OCoLC)960737130  |z (OCoLC)1007770486  |z (OCoLC)1066647722  |z (OCoLC)1378334734 
050 4 |a RC343  |b .E45 2016eb 
060 4 |a WM 170 
072 7 |a HEA  |x 039000  |2 bisacsh 
072 7 |a MED  |x 014000  |2 bisacsh 
072 7 |a MED  |x 022000  |2 bisacsh 
072 7 |a MED  |x 112000  |2 bisacsh 
072 7 |a MED  |x 045000  |2 bisacsh 
082 0 4 |a 616.8  |2 23 
100 1 |a Ellenbroek, B. A.  |q (Bart A.),  |d 1958- 
245 1 0 |a Gene-environment interactions in psychiatry :  |b nature, nurture, neuroscience /  |c Bart Ellenbroek, Jiun Youn. 
260 |a London :  |b Academic Press,  |c �2016. 
300 |a 1 online resource (368) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
588 0 |a Print version record. 
520 |a Gene-Environment Interactions in Psychiatry: Nature, Nurture, Neuroscience begins with the basic aspects of gene-environment studies, such as basic genetics, principles of animals modeling, and the basic processes of how environmental factors affect brain and behavior, with part two describing the most important psychiatric disorders in detail. Each chapter has a similar structure that includes a general description of the disorder that is followed by an analysis of the role of genes and how they are affected by environmental factors. Each chapter ends with a description of the most relevant animal models, again focusing on gene-environment interactions. The book concludes with a critical evaluation of the current research and an outlook for the (possible) future, offering a vignette into the fascinating world of nature, nurture, and neuroscience. 
500 |a Includes index. 
505 0 |a Cover ; Title Page; Copyright Page; Dedication; Contents; Preface; Section I -- General Introduction; Chapter 1 -- Introduction; Introduction; Gregor Johann Mendel; Mendel's first law of inheritance: the law of segregation; Mendel's second law of inheritance: the law of�independent assortment; The legacy of Mendel's work; Criticism of Mendel's work; The search for the Mendelian elements; The sex chromosomes; Beyond Mendel: the historical development of�molecular genetics; A brief history of behavioral genetics; References; Chapter 2 -- The Genetic Basis of Behavior; Introduction. 
505 8 |a The molecular structure of DNADNA synthesis and replication; The structure of the genome; DNA transcription; The structure of genes; mRNA processing; mRNA translation; Genetic alterations; Single Nucleotide Variations; Tandem repeat sequences; Triplet repeats; Variable Number Tandem Repeats (VNTRs); Short insertions and deletions (indels); Copy number variations (CNVs); Chromosomal variations; References; Chapter 3 -- Animal Modelling in Psychiatry; Introduction; Animal models; Screening Models; Pharmacological Bioassays; Neuroscience Bioassays; Simulation Models; Validating animal models. 
505 8 |a Genetic modulation in animalsForward Genetic Approaches; Reverse Genetic Approaches; Random Techniques; Targeted Techniques; References; Chapter 4 -- The Environmental Basis of Behavior; Introduction; Environmental factors; Timing; The prenatal period; The perinatal period; The postnatal period; The adolescent period; Evaluating the role of environmental factors in animals; Developmental differences between rodents and humans; References; Chapter 5 -- Environment Challenges and the Brain; Introduction; Early environmental challenges and structural brain changes. 
505 8 |a Early environmental challenges and the immune systemEarly environmental challenges and the hypothalamic pituitary adrenal (HPA) axis; Early environmental challenges and�neurotransmitter changes; Early environmental challenges and epigenetic changes; The molecular structure of chromosomes; The histone family of proteins; Epigenetic mechanisms -- introduction; Modification at the level of the nucleotides; DNA Methylation; RNA Interference; Chemical modification at the level of the histones; Histone Acetylation; Histone Phosphorylation; Histone Methylation; Additional Histone Modifications. 
505 8 |a The Complexity of Histone ModificationsStructural changes at the level of the nucleosome; Early environmental challenges and epigenetic changes; The Environment and Chromatin Modification; The Environment and Histone Modification; The Environment and Chromatin Remodeling; References; Section II -- Gene-Environment Interactions in Psychiatric Disorders; Chapter 6 -- Drug Addiction; Introduction; Diagnosis and symptoms; The Epidemiology of drug addiction; The neurobiology of drug addiction; The pharmacological treatment of drug addiction; Replacement Therapies; Other Therapies. 
504 |a Includes bibliographical references and index. 
650 0 |a Neurogenetics. 
650 0 |a Psychiatry  |x Genetic aspects. 
650 1 2 |a Mental Disorders  |x genetics  |0 (DNLM)D001523Q000235 
650 2 2 |a Gene-Environment Interaction  |0 (DNLM)D059647 
650 2 2 |a Genetic Predisposition to Disease  |0 (DNLM)D020022 
650 6 |a Neurog�en�etique.  |0 (CaQQLa)201-0102990 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Neurogenetics  |2 fast  |0 (OCoLC)fst01036353 
700 1 |a Youn, Jiun. 
776 0 8 |i Print version :  |z 9780128016572 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128016572  |z Texto completo