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Epigenetic biomarkers and diagnostics /

'Epigenetic Biomarkers and Diagnostics' comprises 32 chapters contributed by leading active researchers in clinical epigenetics. The book is divided into three sections, beginning with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Garc�ia-Gim�enez, Jos�e Luis (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, UK : Academic Press is an imprint of Elsevier, [2016]
Colección:Translational epigenetics series.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Epigenetic biomarkers and diagnostics /  |c edited by Jos�e Luis Garc�ia-Gim�enez. 
264 1 |a London, UK :  |b Academic Press is an imprint of Elsevier,  |c [2016] 
264 4 |c �2016 
300 |a 1 online resource (xvi, 680 pages) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
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338 |a online resource  |b cr  |2 rdacarrier 
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490 1 |a Translational Epigenetics Series 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (ScienceDirect, viewed December 16, 2015). 
505 0 |a Epigenetic Biomarkers: New Findings, Perspectives, and Future Directions in Diagnostics -- The Importance of Biobanks in Epigenetic Studies -- Epigenetic Mechanisms as Key Regulators in Disease: Clinical Implications -- The Evolution of New Technologies and Methods in Clinical Epigenetics Research -- Biomarkers and Methodologies for Monitoring Epigenetic Drug Effects in Cancer -- Genome-Wide Techniques for the Study of Clinical Epigenetic Biomarkers -- Sequenom MassARRAY Technology for the Analysis of DNA Methylation: Clinical Applications -- The Role of Methylation-Specific PCR and Associated Techniques in Clinical Diagnostics -- Pyrosequencing and Its Application in Epigenetic Clinical Diagnostics -- Mass Spectrometry for the Identification of Posttranslational Modifications in Histones and Its Application in Clinical Epigenetics -- High-Throughput Analysis of Noncoding RNAs: Implications in Clinical Epigenetics -- Circulating Noncoding RNAs as Clinical Biomarkers -- DNA Methylation Biomarkers in Lung Cancer -- DNA Methylation Alterations as Biomarkers for Prostate Cancer -- DNA Methylation in Breast Cancer -- DNA Methylation in Obesity and Associated Diseases -- DNA Methylation Biomarkers in Asthma and Allergy -- DNA Methylation for Prediction of Adverse Pregnancy Outcomes -- Epigenetics in Infectious Diseases -- DNA Methylation in Neurodegenerative Diseases -- The Histone Code and Disease: Posttranslational Modifications as Potential Prognostic Factors for Clinical Diagnosis -- Histone Posttranslational Modifications and Chromatin Remodelers in Prostate Cancer -- Histone Posttranslational Modifications in Breast Cancer and Their Use in Clinical Diagnosis and Prognosis -- Histone Variants and Posttranslational Modifications in Spermatogenesis and Infertility -- Circulating Histones and Nucleosomes as Biomarkers in Sepsis and Septic Shock -- Chromatin Landscape and Epigenetic Signatures in Neurological Disorders: Emerging Perspectives for Biological and Clinical Research -- MicroRNA Deregulation in Lung Cancer and Their Use as Clinical Tools -- Circulating Nucleic Acids as Prostate Cancer Biomarkers -- MicroRNAs in Breast Cancer and Their Value as Biomarkers -- MicroRNAs in Bone and Soft Tissue Sarcomas and Their Value as Biomarkers -- miRNAs in the Pathophysiology of Diabetes and Their Value as Biomarkers -- Index. 
520 8 |a 'Epigenetic Biomarkers and Diagnostics' comprises 32 chapters contributed by leading active researchers in clinical epigenetics. The book is divided into three sections, beginning with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. The second section refers to the importance of the sample quality and ethical issues in clinical epigenetics, with the final section presenting the technologies and methods to discover and analyze epigenetic biomarkers. 
650 0 |a Epigenetics. 
650 0 |a Biochemical markers. 
650 2 |a Epigenesis, Genetic  |0 (DNLM)D044127 
650 2 |a Biomarkers  |0 (DNLM)D015415 
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700 1 |a Garc�ia-Gim�enez, Jos�e Luis,  |e editor. 
776 0 8 |i Print version:  |a Garcia-Gimenez, Jose Luis.  |t Epigenetic Biomarkers and Diagnostics.  |d Saint Louis, MO : Elsevier Science, �2015  |z 9780128018996 
830 0 |a Translational epigenetics series. 
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