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Recent advances in medicinal chemistry. Volume 1 /
Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets,...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier Ltd.,
[2014]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Recent Advances in Medicinal Chemistry, Volume 1; Copyright; Contents ; Foreword ; Preface ; List of Contributors ; Chapter 1: New Functions of Old Drugs: Aureolic Acid Group of Anti-Cancer Antibiotics and Non-Steroidal Anti-Inflammatory Drugs ; Abstract ; 1. Introduction ; 2. Principal Functions of Nsaids and Aureolic Acid Anticancer Antibiotics and Their Mechanism of Action ; 3. Other Functions of These Drugs and Mechanism of Actions ; 4. Chemical Dissection of the Drugs to Understand Alternate Functions ; 5. Conclusion ; Acknowledgements ; Conflict of Interest ; Disclosure
- Chapter 3: Characterization of Inorganic Nanomaterials as Therapeutic Vehicles Abstract ; Introduction ; Concluding Remarks ; Acknowledgements ; Conflict of Interest ; Disclosure ; References ; Chapter 4: Aromatase Inhibitors: A New Reality for the Adjuvant Endocrine Treatment of Early-Stage Breast Cancer in Postmenopausal Women ; Abstract ; Introduction ; Conclusions ; Acknowledgements ; Conflict of Interest ; Disclosure ; References ; Chapter 5: Bacterial FabH: Towards the Discovery of New Broad-Spectrum Antibiotics ; Abstract ; Introduction ; Bacterial Type II Fas the Biological Process
- Three Dimensional Structure of FabH Substrate Binding and Specificity ; Catalytic Mechanism and Substrate Binding ; Molecular Modeling Studies of FabH ; Concluding Remarks ; Acknowledgements ; Conflict of Interest ; Disclosure ; References ; Chapter 6: Tannins and Their Influence on Health ; Abstract ; 1. Introduction ; 2. Classification of Tannins ; 3. Absorption and Metabolism of Tannins ; 4. Biological Activity ; 5. Human Intervention Studies ; 6. Adverse and Undesirable Effects ; 7. Conclusions ; Acknowledgements ; Conflict of Interest ; Disclosure ; Abbreviations ; References
- Chapter 7: Rho-GTPases and Statins: A Potential Target and a Potential Therapeutic Tool Against Tumors? Abstract ; Introduction ; Role of RhoA in Normal and Tumor Cells ; Statins Inhibit RhoA Activity ; Statins and Tumor Growth/apoptosis ; Statins and Angiogenesis ; Statins and Metastasis ; Statins, Chemotherapy Efficacy and Multidrug Resistance ; Statins and Chemoprevention of Tumors ; Statins in Cancer Treatment ; Acknowledgements ; Conflict of Interest ; Disclosure ; References ; Chapter 8: Carotenoids that are Involved in Prostate Cancer Risk ; Abstract ; Introduction