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Protein kinase inhibitors in research and medicine. Volume 548 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier Academic Press,
2014.
|
| Edición: | First edition. |
| Colección: | Methods in enzymology ;
v. 548. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Catalytic mechanisms and regulation of protein kinases / Zhihong Wang and Philip A. Cole
- A structural atlas of kinases inhibited by clinically approved drugs / Qi Wang, Julie A. Zorn, and John Kuriyan
- Fragment-based approaches to the discovery of kinase inhibitors / Paul N. Mortenson, Valerio Berdini, and Marc O'Reilly
- Targeting protein kinases with selective and semipromiscuous covalent inhibitors / Rand M. Miller and Jack Taunton
- The resistance tetrad : amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles / Fiona P. Bailey, Veselin I. Andreev, and Patrick A. Eyers
- FLiK : a direct-binding assay for the identification and kinetic characterization of stabilizers of inactive kinase conformations / Jeffrey R. Simar and Daniel Rauh
- Discovery of allosteric Bcr-Abl inhibitors from phenotypic screen to clinical candidate / Nathanael S. Gray and Doriano Fabbro
- The logic and design of analog-sensitive kinases and their small molecule inhibitors / Michael S. Lopez, Joseph I. Kliegman, and Kevan M. Shokat.