Cargando…

Studies in natural products chemistry. Volume 44 /

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Rahman, Atta-ur-, 1942- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier, 2015.
Colección:Studies in Natural Products Chemistry ; 44
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

LEADER 00000cam a2200000 a 4500
001 SCIDIR_ocn896856737
003 OCoLC
005 20231120111915.0
006 m o d
007 cr |||||||||||
008 141104r20152014ne ob 001 0 eng d
040 |a UKMGB  |b eng  |e pn  |c UKMGB  |d OCLCO  |d N$T  |d OPELS  |d E7B  |d OCLCF  |d OPELS  |d YDXCP  |d CDX  |d OCLCQ  |d DEBBG  |d OCLCQ  |d Z5A  |d VGM  |d U3W  |d D6H  |d LQU  |d UHL  |d UKMGB  |d S2H  |d OCLCO  |d UIU  |d OCLCO  |d OCLCQ  |d OCLCO 
015 |a GBB4C8123  |2 bnb 
016 7 |a 016941231  |2 Uk 
019 |a 1105177827  |a 1105566243  |a 1282301860 
020 |a 9780444634702  |q (electronic bk.) 
020 |a 0444634703  |q (electronic bk.) 
020 |z 9780444634603  |q (hbk.) 
020 |z 0444634606  |q (hbk.) 
035 |a (OCoLC)896856737  |z (OCoLC)1105177827  |z (OCoLC)1105566243  |z (OCoLC)1282301860 
050 4 |a QD415 
072 7 |a SCI  |x 007000  |2 bisacsh 
082 0 4 |a 572  |2 23 
245 0 0 |a Studies in natural products chemistry.  |n Volume 44 /  |c volume editor, Atta-ur- Rahman. 
264 1 |a Amsterdam :  |b Elsevier,  |c 2015. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 0 |a Studies in Natural Products Chemistry ;  |v 44 
504 |a Includes bibliographical references and index. 
588 0 |a CIP data; resource not viewed. 
520 |a Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. 
505 0 |a Cover; Title Page; Copyright Page; Contents; Contributors; Preface; Chapter 1 -- Terpenoids and Sterols from Mushrooms; Introduction; Sesquiterpenoids; Lactarane-Type Sesquiterpenoids; Marasmane-Type Sesquiterpenoids; Nardosinane-Type and Aristolane-Type Sesquiterpenoids; Protoilludane-Type Sesquiterpenoids; Russulane-Type Norsesquiterpenoids; Triterpenoids; Lanostane-Type Triterpenoids; Cucurbitane-Type Triterpenoids; Sterols; Sterols Bearing 5a,6a-Epoxy Group; Sterols Bearing 5a,9a-Epidioxy and 5b,9b-Dihydroxy Groups; Sterols Bearing Enone, Diene, and Ketone Moieties 
505 8 |a Sterols Bearing 3b,5a,6b,7a-Tetrahydroxy, 3b,5a,6a,9a-Tetrahydroxy, and 3b,5a,6b,9a-Tetrahydroxy Groups23-Methylergostane-Type Sterols; Sterols Bearing 1,2,3,4,5,10,19-Heptanor Structure; Meroterpenoids; Conclusions; Abbreviations; References; Chapter 2 -- From Bench to Bedside: Natural Products and Analogs for the Treatment of Neglected Tropical Diseases (NTDs); Introduction; Neglected Tropical Diseases; Tuberculosis; Leishmaniasis; Malaria; Chagas Disease (American Trypanosomiasis); Human African Trypanosomiasis (Sleeping Sickness); Dengue; Lymphatic Filariasis (Elephantiasis); Helminthiasis 
505 8 |a Leprosy (Hansen Disease)Trachoma; Buruli Ulcer; Schistosomiasis; Conclusions; Abbreviations; References; Chapter 3 -- Febrifugine and Its Analogs: Studies for Their Antimalarial and Other Therapeutic Properties; Introduction; Discovery; Structure Elucidation; Chemical and physical Properties of Febrifugine; Synthesis of Febrifugine; Pharmacology of Febrifugine; Antimalarial Activity of Febrifugine; Anticoccidial Activity; Toxicity; Febrifugine Analogs; Halofuginone; Antimalarial Properties; Coccidiosis; Autoimmune Diseases; Other Diseases; Polypharmacy; Abbreviations; Concluding Remarks 
505 8 |a AcknowledgmentsReferences; Chapter 4 -- Macrocyclic N-Methylated Cyclic Peptides and Depsipeptides; Introduction; Aureobasidins; Introduction; Isolation; Classification of Abs; Structural Determination; Biological Activity; Synthesis; Total Synthesis of Abs; Semisynthesis of Abs; Cyclosporins; Introduction; Isolation; Classification of Cs; Structural Determination; Biological Activity; Synthesis; Synthesis of Cyclosporins; Synthesis of Unusual Amino Acid MeBmt; Dolastatin; Introduction; Isolation; Classification of Cyclic Peptides; Cyclopeptides; Cyclodepsipeptides; Structure Determination 
505 8 |a Biological ActivitySynthesis; Didemnins; Introduction; Isolation; Classification of Didemnins; Structural Determination; Biological Activity; Synthesis; Total Syntheses of Didemnin, the Natural Products; Syntheses of Didemnin Analogs; Miscellaneous Cyclopeptides and Cyclodepsipeptide; Introduction; Omphalotins; Petriellin; Clavariopsins; Somamides; Salinamides; Abbreviations; Conclusion; References; Chapter 5 -- Anticancer Drugs and Potential Anticancer Leads Inspired by Natural Products; Introduction; Tubulin/Microtubule-Targeted Anticancer Agents 
650 0 |a Bioorganic chemistry. 
650 0 |a Bioactive compounds. 
650 0 |a Natural products. 
650 6 |a Chimie bio-organique.  |0 (CaQQLa)201-0150662 
650 6 |a Compos�es bioactifs.  |0 (CaQQLa)201-0046484 
650 6 |a Produits naturels.  |0 (CaQQLa)201-0030192 
650 7 |a SCIENCE  |x Life Sciences  |x Biochemistry.  |2 bisacsh 
650 7 |a Bioactive compounds  |2 fast  |0 (OCoLC)fst00831933 
650 7 |a Bioorganic chemistry  |2 fast  |0 (OCoLC)fst00832648 
650 7 |a Natural products  |2 fast  |0 (OCoLC)fst01034390 
700 1 |a Rahman, Atta-ur-,  |d 1942-  |e editor. 
776 0 8 |i Print version:  |t Studies in natural products chemistry. Volume 44  |z 9780444634603  |w (OCoLC)913791672 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780444634603  |z Texto completo 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/bookseries/15725995/44  |z Texto completo