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Alcohol and the nervous system /

Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol''s effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscien...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Sullivan, Edith V. (Editor ), Pfefferbaum, Adolf (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Edinburgh : Elsevier, 2014.
Colección:Handbook of clinical neurology ; v. 125.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Alcohol and the nervous system /  |c volume editors, Edith V. Sullivan and Adolf Pfefferbaum. 
264 1 |a Edinburgh :  |b Elsevier,  |c 2014. 
300 |a 1 online resource :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Handbook of clinical neurology ;  |v volume 125 
588 0 |a Online resource; title from PDF title page (EBSCO, viewed October 15, 2014). 
504 |a Includes bibliographical references and index. 
505 0 |a Front Cover; Alcohol and the Nervous System; Copyright; Handbook of Clinical Neurology 3rd Series; Foreword; Preface; Contributors; Contents; Section 1: Introduction; Chapter 1: Alcoholism: Diagnosis, Prognosis, Epidemiology, and Burden Of the Disease; Natural History and Clinical Assessment; Alcoholism Frequency; Practical Typology; Diagnosis; Alcohol Use History; Making a Diagnosis; Physiologic Dependence: Tolerance And withdrawal; Tolerance; Withdrawal; Loss of Control Phenomenon; Social Or Physical Decline; Gauging Prognosis; Positive Versus Negative; Diagnosis is Prognosis. 
505 8 |a Abuse Rather than DependenceBehavioral Versus Hepatic Diagnosis; Assessing Ambivalence and Continuing Loss Of Control risk; Social Stability; Vaillant''s Four Prognostic Factors; Structured time; A Rehabilitation Relationship; Sources of Hope Or self-esteem; A Negative Behavioral Reinforcer; Summing Up Prognosis; Other Psychiatric Assessment; Dsm-5 and Alcoholism Diagnosis: Progress Or Old Wine in a New Bottle?; Economic Costs of Problematic Alcohol use; Cost of Illness: Clarifying the Concept; Cost: Contribution By Category; Interpretation: Cost Consequences; Economics and Alcohol. 
505 8 |a Alcohol-related Spending and Other Disease CategoriesConclusion; References; Chapter 2: Perspectives on the Neuroscience of Alcohol From the National Institute on Alcohol Abuse and Alcoholism; Introduction; The Division of Neuroscience and Behavior (Dnb) and Its Mission; Genetics; Neuroadaptation; Behavior; Neurobehavioral, Structural, and Functional Consequences of Human Alcoholism; Preclinical Medications Development; Future Directions; References; Section 2: Animal Models: Neurochemistry and Metabolism of Alcohol; Chapter 3: Neurocircuitry of Alcohol Addiction: Synthesis From animal models. 
505 8 |a Definitions and Conceptual Framework for Neurocircuitry of AlcoholismAnimal Models for Compulsive Alcohol Seeking; Animal Models of Motivation, Withdrawal, and Opponent Process; Neurocircuits for the Binge/intoxication Stage Associated With Alcoholism; Neural Substrates for the Withdrawal/negative Affect Stage Associated With Alcoholism; Within-system Neuroadaptations That Contribute to the Compulsivity Associated With the Dark Side of Alcoholism; Between-system Neuroadaptations That Contribute to Compulsivity Associated With the Dark Side of Alcoholism. 
505 8 |a Neural Substrates for Executive Function Deficits Associated With alcoholismCompulsivity in Alcoholism: An allostatic view; Acknowledgments; References; Chapter 4: Metabolism; Overview; Ethanol Metabolism; Hepatic Ethanol Metabolism; Genetic Factors: Genetic Variants And gender; Genetic Variation in Adh, Aldh2, Cyp2E1 and Ethanol Metabolism; Genetic Predisposition to Alcoholism; Effects of Gender on Alcohol Metabolism; Fasting; Protein Malnutrition; Effect of Fat Content Or Composition Of diet; Effect of Dietary Ethanol; Miscellaneous Dietary Effects; Endocrine Effects. 
520 |a Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol''s effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol''s effect on the central nervous system, the diagn. 
650 0 |a Alcohol  |x Physiological effect. 
650 0 |a Alcohol  |x Toxicology. 
650 1 2 |a Alcohol-Induced Disorders, Nervous System  |0 (DNLM)D020268 
650 2 |a Alcoholic Intoxication  |0 (DNLM)D000435 
650 2 2 |a Alcoholic Beverages  |x toxicity  |0 (DNLM)D000434Q000633 
650 2 2 |a Alcohol-Related Disorders  |x pathology  |0 (DNLM)D019973Q000473 
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655 4 |a Internet Resources. 
700 1 |a Sullivan, Edith V.,  |e editor. 
700 1 |a Pfefferbaum, Adolf,  |e editor. 
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