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Calcium and cell function. Volume VI /
Calcium and Cell Function.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Orlando ; London :
Academic Press,
1986.
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| Colección: | Molecular biology.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Calcium and Cell Function; Copyright Page; Table of Contents ; Contributors; Preface; Contents of Previous Volumes; Chapter 1. Peptides Recognizing Calmodulin; I. Introduction; II. Methods for the Determination of Peptide-Calmodulin Interaction in Vitro; III. Overview of Calmodulin-Binding Peptides; IV. Competitive Relationships and Stoichiometry; V. Peptide Binding by Proteolytic Fragments of Calmodulin; VI. Peptide Associations with Proteins Related to Calmodulin; VII. Do Calmodulin and the cAMP-Dependent Protein Kinase Act on Similar Recognition Sequences?
- VIII. Peptides as Structural and Spectroscopic Probes of CalmodulinIX. Peptides as Useful Calmodulin Antagonists; X. Summary; References; Chapter 2. Molecular and Regulatory Properties of Calmodulin-Dependent Phosphodiesterase from Brain; I. Introduction; II. Enzymatic and Physical Properties of Phosphodiesterase; III. Use of Calmodulin Derivatives to Probe the Mechanism of Calmodulin Activation; IV. Future Directions; References; Chapter 3. Calmodulin-Dependent Protein Phosphatase; I. Introduction; II. Historical Background; III. Assay; IV. Distribution; V. Purification.
- VI. Molecular PropertiesVII. Identification of the Catalytic Subunit; VIII. Stimulation by Calcium and Calmodulin; IX. Stimulation by Limited Trypsinization; X. Regulation by Divalent Cations; XI. Deactivation by Calcium and Calmodulin; XII. Substrate Specificity; XIII. Concluding Remarks; References; Chapter 4. Biophysical Studies of Calmodulin; I. Introduction; II. Proteolytic and Chemical Modification of CaM; III. Calcium-Binding Studies; IV. Thermochemical Studies; V. Stopped-Flow Kinetic Studies of CaM and Its Proteolytic Fragments; VI. NMR and ESR Studies.
- VII. Fluorescence and Luminescence StudiesVIII. Localization of Interaction Sites on Calmodulin; IX. Concluding Remarks; References; Chapter 5. Regulation of Ca2 + -Dependent Proteinase of Human Erythrocytes; I. Introduction; II. The Proteolytic Enzymes of Human Erythrocytes; III. Physical Properties; IV. Effect of High Concentrations of Calcium Ions on the Activity of Calpain; V. Effect of Substrate on the Conversion of Procalpain to Active Calpain at Micromolar Ca2+ Concentrations; VI. The Molecular Basis of the Conversion of Procalpain to Active Calpain.
- VII. Mechanism of Procalpain ActivationVIII. Specificity and Selectivity of Proteolytic Digestion by Calpain; IX. Regulation of Human Erythrocyte Calpain; X. Physiological Function of Calpain in Human Erythrocytes; References; Chapter 6. Toxicological Implications of Perturbation of Ca2 + Homeostasis in Hepatocytes; I. Introduction; II. Calcium and Tissue Toxicity; III. Calcium Compartmentation in the Hepatocyte; IV. Methods Used to Study Calcium Compartmentation in Hepatocytes; V. Perturbation of Calcium Homeostasis during Oxidative Cell Injury.