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| LEADER |
00000cam a2200000 i 4500 |
| 001 |
SCIDIR_ocn889675352 |
| 003 |
OCoLC |
| 005 |
20231120111719.0 |
| 006 |
m o d |
| 007 |
cr cnu---unuuu |
| 008 |
140830s2013 enka ob 001 0 eng d |
| 040 |
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|a EBLCP
|b eng
|e pn
|c EBLCP
|d OCLCO
|d N$T
|d GZM
|d MYG
|d UIU
|d OCLCF
|d OPELS
|d OCLCQ
|d U3W
|d D6H
|d OCLCQ
|d S2H
|d OCLCO
|d OCLCQ
|d OCLCO
|d OCLCQ
|d OCLCO
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| 020 |
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|a 9781908818287
|q (electronic bk.)
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| 020 |
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|a 190881828X
|q (electronic bk.)
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| 020 |
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|z 9781907568213
|q (print)
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| 035 |
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|a (OCoLC)889675352
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| 050 |
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4 |
|a RM301.25
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| 072 |
|
7 |
|a MED
|x 071000
|2 bisacsh
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| 082 |
0 |
4 |
|a 615.19
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| 100 |
1 |
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|a Lai, Yurong.
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| 245 |
1 |
0 |
|a Transporters in drug discovery and development :
|b detailed concepts and best practice /
|c Yurong Lai.
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| 260 |
|
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|a Oxford :
|b Elsevier Science,
|c 2013.
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| 300 |
|
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|a 1 online resource (xxiii, 734 pages) :
|b illustrations
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Woodhead Publishing Series in Biomedicine
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| 504 |
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|a Includes bibliographical references and index.
|
| 588 |
0 |
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|a Print version of record.
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| 505 |
0 |
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|a Membrane transporters and the diseases corresponding to functional defects -- P-glycoprotein (P-gp/MDR1)/ABCB1 -- Multidrug resistanceassociated protein 2 (MRP2/ABCC2) -- Breast cancer resistance protein (BCRP)/ABCG2 -- The bile salt export pump (BSEP/ABCB11) -- Organic aniontransporting polypeptides (OATPs/SLCOs) -- Organic anion, organic cation and zwitterion transporters of the SLC22 and SLC47 superfamily (OATs, OCTs, OCTNs and MATEs) -- Drug transporters in drug discovery and development -- 9 Transporter study methodologies.
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| 500 |
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|a Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery.
|
| 650 |
|
0 |
|a Biopharmaceutics.
|
| 650 |
|
0 |
|a Drug development.
|
| 650 |
|
0 |
|a Drugs
|x Design.
|
| 650 |
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2 |
|a Biopharmaceutics
|0 (DNLM)D001702
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| 650 |
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2 |
|a Drug Design
|0 (DNLM)D015195
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| 650 |
|
6 |
|a Biopharmacie.
|0 (CaQQLa)201-0050334
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| 650 |
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6 |
|a M�edicaments
|x D�eveloppement.
|0 (CaQQLa)201-0306620
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| 650 |
|
6 |
|a M�edicaments
|x Conception.
|0 (CaQQLa)201-0203461
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| 650 |
|
7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
|
| 650 |
|
7 |
|a Biopharmaceutics
|2 fast
|0 (OCoLC)fst00832650
|
| 650 |
|
7 |
|a Drug development
|2 fast
|0 (OCoLC)fst00898670
|
| 650 |
|
7 |
|a Drugs
|x Design
|2 fast
|0 (OCoLC)fst00898790
|
| 776 |
0 |
8 |
|i Print version:
|a Lai, Yurong.
|t Transporters in Drug Discovery and Development : Detailed Concepts and Best Practice.
|d Burlington : Elsevier Science, �2013
|z 9781907568213
|
| 830 |
|
0 |
|a Woodhead Publishing series in biomedicine.
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9781907568213
|z Texto completo
|
