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140315t20142014enkaf ob 001 0 eng d |
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|a 900282785
|a 1066614535
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|q (electronic bk.)
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|z 9780128001745
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|z 0128001747
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|a (OCoLC)876042826
|z (OCoLC)900282785
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|a QP188.P26
|b .P36 2014eb
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|a 612.34
|2 23
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|a Pancreatic beta cell.
|n Volume 95,
|p Vitamins and hormones /
|c Gerald Litwack, series editor.
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264 |
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|a London, England :
|b Academic Press,
|c 2014.
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264 |
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|c �2014
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300 |
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|a 1 online resource (517 pages, plates) :
|b illustrations.
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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490 |
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|a Vitamins and hormones ;
|v volume ninety five
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|a Includes bibliographical references and index.
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|a Online resource; title from PDF title page (ebrary, viewed March 10, 2014).
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|a 1. Overview of Insulin Biosynthesis in Pancreatic Beta Cells2. Proinsulin Entry into the ER; 2.1. Secretory protein translocation into the ER; 2.2. Preproinsulin recognition and targeting to the ER; 2.3. Preproinsulin translocation across the ER membrane; 2.4. Coordination between preproinsulin signal peptide cleavage and downstream proinsulin folding; 2.5. Pancreatic beta cell failure and diabetes caused by defects in some of the earliest events of insulin biosynthesis; 3. Proinsulin Transit Through the ER; 3.1. Proinsulin oxidative folding in the ER; 3.2. Quality control and ER exit
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|a 4. Physiology and Pathophysiology of Ionic Channels4.1. ATP-sensitive potassium channels; 4.1.1. KATP channels mutation; 4.1.2. KATP in metabolic syndrome; 4.2. Transient receptor potential channels; 4.3. Voltage-gated Na+ channels; 4.4. Voltage-dependent calcium channels; 4.5. Returning to resting potential; 4.6. Calcium release from intracellular reservoirs; 5. Concluding Remarks; References; Chapter Five: The Beta Cell Immunopeptidome; 1. Introduction; 2. Autoantigens in T1D; 3. Antigen Processing; 3.1. Class I presentation; 3.2. Class II presentation; 4. Identifying T Cell Epitopes in T1D
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|a First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Key features: Expertise of the c.
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|a Pancreatic beta cells.
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650 |
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|a Islets of Langerhans
|0 (DNLM)D007515
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|a Cellules b�eta des �ilots de Langerhans.
|0 (CaQQLa)201-0368294
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650 |
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|a MEDICAL
|x Physiology.
|2 bisacsh
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650 |
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|a SCIENCE
|x Life Sciences
|x Human Anatomy & Physiology.
|2 bisacsh
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650 |
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|a Pancreatic beta cells
|2 fast
|0 (OCoLC)fst01051997
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700 |
1 |
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|a Litwack, Gerald.
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776 |
0 |
8 |
|i Print version:
|t Pancreatic beta cell. Volume 95, Vitamins and hormones.
|d London, England : Academic Press, �2014
|h xviii, 482 pages
|z 9780128001745
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830 |
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|a Vitamins and hormones ;
|v v. 95.
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856 |
4 |
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|u https://sciencedirect.uam.elogim.com/science/book/9780128001745
|z Texto completo
|