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Pancreatic beta cell. Volume 95, Vitamins and hormones /

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is rel...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Litwack, Gerald
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, England : Academic Press, 2014.
Colección:Vitamins and hormones ; v. 95.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Pancreatic beta cell.  |n Volume 95,  |p Vitamins and hormones /  |c Gerald Litwack, series editor. 
264 1 |a London, England :  |b Academic Press,  |c 2014. 
264 4 |c �2014 
300 |a 1 online resource (517 pages, plates) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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490 1 |a Vitamins and hormones ;  |v volume ninety five 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (ebrary, viewed March 10, 2014). 
505 8 |a 1. Overview of Insulin Biosynthesis in Pancreatic Beta Cells2. Proinsulin Entry into the ER; 2.1. Secretory protein translocation into the ER; 2.2. Preproinsulin recognition and targeting to the ER; 2.3. Preproinsulin translocation across the ER membrane; 2.4. Coordination between preproinsulin signal peptide cleavage and downstream proinsulin folding; 2.5. Pancreatic beta cell failure and diabetes caused by defects in some of the earliest events of insulin biosynthesis; 3. Proinsulin Transit Through the ER; 3.1. Proinsulin oxidative folding in the ER; 3.2. Quality control and ER exit 
505 8 |a 4. Physiology and Pathophysiology of Ionic Channels4.1. ATP-sensitive potassium channels; 4.1.1. KATP channels mutation; 4.1.2. KATP in metabolic syndrome; 4.2. Transient receptor potential channels; 4.3. Voltage-gated Na+ channels; 4.4. Voltage-dependent calcium channels; 4.5. Returning to resting potential; 4.6. Calcium release from intracellular reservoirs; 5. Concluding Remarks; References; Chapter Five: The Beta Cell Immunopeptidome; 1. Introduction; 2. Autoantigens in T1D; 3. Antigen Processing; 3.1. Class I presentation; 3.2. Class II presentation; 4. Identifying T Cell Epitopes in T1D 
520 |a First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Key features: Expertise of the c. 
650 0 |a Pancreatic beta cells. 
650 2 |a Islets of Langerhans  |0 (DNLM)D007515 
650 6 |a Cellules b�eta des �ilots de Langerhans.  |0 (CaQQLa)201-0368294 
650 7 |a MEDICAL  |x Physiology.  |2 bisacsh 
650 7 |a SCIENCE  |x Life Sciences  |x Human Anatomy & Physiology.  |2 bisacsh 
650 7 |a Pancreatic beta cells  |2 fast  |0 (OCoLC)fst01051997 
700 1 |a Litwack, Gerald. 
776 0 8 |i Print version:  |t Pancreatic beta cell. Volume 95, Vitamins and hormones.  |d London, England : Academic Press, �2014  |h xviii, 482 pages  |z 9780128001745 
830 0 |a Vitamins and hormones ;  |v v. 95. 
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