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Development and function of myeloid subsets Volume 120 /

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecul...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Murphy, Kenneth (Kenneth M.), Merad, Miriam
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier/Academic Press, 2013.
Edición:First edition.
Colección:Advances in immunology ; v. 120.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Development and function of myeloid subsets  |n Volume 120 /  |c edited by Kenneth M. Murphy, Washington University, School of Medicine, St. Louis, Missouri, USA, Miriam Merad, Icahn School of Medicine at Mount Sinai, New York, USA. 
250 |a First edition. 
264 1 |a Amsterdam :  |b Elsevier/Academic Press,  |c 2013. 
300 |a 1 online resource (339 pages) :  |b color illustrations 
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490 1 |a Advances in immunology,  |x 0065-2776 ;  |v v. 120 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (ebrary, viewed October 14, 2013). 
505 0 |a Front Cover; Development and Function of Myeloid Subsets; Copyright; Contents; Contributors; Chapter One: Ontogeny and Functional Specialization of Dendritic Cells in Human and Mouse; 1. Introduction; 2. History of DC Identification and Characterization; 2.1. Mouse DCs; 2.2. Human DCs; 2.3. Classification of mouse and human DCs; 3. Recent Advances in Mouse DC Immunobiology: Lessons from a Rodent; 3.1. Origin and differentiation of mouse DCs; 3.2. CD8+/CD103+ DC lineage; 3.3. CD11b+ DCs; 3.4. Plasmacytoid DCs; 3.5. Langerhans cells; 3.6. Inflammatory DCs 
505 8 |a 4. Recent Advances in Human DC Immunobiology4.1. Origin and differentiation of human DCs; 4.2. Myeloid CD141hi DCs; 4.3. Myeloid CD1c+ DCs; 4.4. CD14+ DCs; 4.5. Plasmacytoid DCs; 4.6. Langerhans cells; 4.7. Slan DCs; 4.8. Inflammatory DCs; 5. Humanized Mice; 6. Matching Mice and Men; 6.1. Interspecies parallels; 6.2. Interspecies differences; 7. The Relationship of DCs to Monocytes and Macrophages; 8. Next Steps Ahead; 9. Disclosure Statement; Acknowledgments; References; Chapter Two: Dendritic Cell Migration Through the Lymphatic Vasculature to Lymph Nodes 
505 8 |a 1. Structure and Function of the Lymphatic Vasculature2. DC Migration into Lymphatics and the Requirement for Specialized Lymphatic Capillaries; 3. DC Mobilization to LNs: The Role of CCR7; 4. DC Mobilization to LNs: The Machinery for Locomotion; 5. Lymphangiogenesis and DC Trafficking During Inflammation; 6. Concluding Remarks; References; Chapter Three: A Close Encounter of the Third Kind: Monocyte-Derived Cells; 1. Dendritic Cell and Macrophages; 1.1. Classical macrophages; 1.2. Classical dendritic cells; 2. Monocytes, the Mononuclear Phagocytes of the Blood Compartment 
505 8 |a 3. Monocytes, as Precursors of Tissue Mononuclear Phagocytes3.1. Effector monocytes; 3.2. Monocyte-derived dendritic cells; 3.3. Monocyte-derived macrophages; 4. Monocyte-Derived Cells in the Inflamed Peritoneum; 5. Monocyte-Derived Cells in the Inflamed Brain; 6. Monocyte-Derived Cells in the Intestine; 7. Development of Monocyte-Derived Cells; 8. Perspective; Acknowledgment; References; Chapter Four: Plasmacytoid Dendritic Cell Development; 1. Background; 2. Markers for pDC Identification; 3. Cytokines Promoting pDC Development; 4. Transcription Factors Determining pDC Development 
505 8 |a 5. Early Investigation of the Myeloid Versus Lymphoid Origin of pDC6. Markers of pDC of Lymphoid Origin?; 7. CDP and the Consensus Myeloid Pathway to pDC; 8. Reassessment of the Lymphoid Pathway to pDC; 9. Implications of RAG-1 Expression and IgH Gene Rearrangements in pDC; 10. Extension of the CDP Definition to Include New pDC Precursors; 11. A Different Non-pDC but pDC-Like Product of the Myeloid Pathway; 12. Tracking pDC Development Using Cellular ``Barcoding� � ; 13. Some Conclusions; References 
520 |a Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Key features: * Contributions from leading authorities * Informs and updates on all the latest devel. 
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650 0 |a Leucocytes. 
650 0 |a Immunology. 
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700 1 |a Murphy, Kenneth  |q (Kenneth M.) 
700 1 |a Merad, Miriam. 
776 0 8 |i Print version:  |z 9781299923874 
830 0 |a Advances in immunology ;  |v v. 120. 
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