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Between the lines of genetic code : genetic interactions in understanding disease and complex phenotypes /

Between the Lines of Genetic Code lays out methodologies and tools for the measurement and evaluation of gene-gene and gene-environment studies and gives perspective on the future of this discipline. The book begins by defining terms for interaction studies, describing methodologies, and critically...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Padyukov, Leonid
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier/AP, �2014.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Terminology and definitions for interaction studies
  • Reducing dimensionality in the search for gene-gene interactions
  • Study design for interaction analyses
  • High-throughput genetic interaction study
  • Gene-gene and gene : environmental interaction in rheumatoid arthritis
  • Genetic and environmental risk factors for multiple sclerosis : a role for interaction analysis
  • Gene-gene and gene : environmental interactions in defining risk and spectrum of phenotypes in idiopathic inflammatory myopathies
  • Functional studies of gene-gene interaction of autoimmune diseases
  • Genetic vectors approach in a study of fine structure of interaction between risk haplotype of HTR2A and HLA-DRB1 shared epitope alleles in rheumatoid arthritis
  • Network biology empowering detection and understanding of interactions between genetic factors in development of complex phenotypes
  • Conclusions.