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Ubiquitin and protein degradation. Part B /
Ubiquitin and Protein Degradation, Part B will cover chemical biology, ubiquitin derivatives and ubiquitin-like proteins, deubiquitinating enzymes, proteomics as well as techniques to monitor protein degradation. The chapters are highly methodological and focus on application of techniques. *Second...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Elsevier Academic Press,
2005.
|
| Colección: | Methods in enzymology ;
vol. 399. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
| LEADER | 00000cam a2200000Ma 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn846753139 | ||
| 003 | OCoLC | ||
| 005 | 20231117044900.0 | ||
| 006 | m o d | ||
| 007 | cr ||||||||||| | ||
| 008 | 051025s2005 cauaf ob 001 0 eng d | ||
| 040 | |a KIJ |b eng |e pn |c KIJ |d OCLCF |d OCLCO |d KUK |d YDXCP |d OCLCQ |d OCLCO |d TEF |d OPELS |d OCLCQ |d OCL |d OCLCQ |d UAB |d KIJ |d OCLCQ |d OCLCO |d ANS |d ESU |d YOU |d OCLCO |d OCLCA |d SOI |d OCLCO |d OCLCQ |d WURST |d OCLCA |d QGK |d OCLCO |d AAA |d OCLCO | ||
| 019 | |a 1125507439 |a 1243078202 | ||
| 020 | |z 0121828042 | ||
| 020 | |z 9780121828042 | ||
| 035 | |a (OCoLC)846753139 |z (OCoLC)1125507439 |z (OCoLC)1243078202 | ||
| 050 | 4 | |a QP551.6 | |
| 060 | 4 | |a QU135 |b MET | |
| 082 | 0 | 4 | |a 572/.6 |2 23 |
| 245 | 0 | 0 | |a Ubiquitin and protein degradation. |n Part B / |c edited by Raymond J. Deshaies. |
| 260 | |a San Diego : |b Elsevier Academic Press, |c 2005. | ||
| 300 | |a 1 online resource (xli, 907 pages, [34 pages of color plates]). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a data file |2 rda | ||
| 490 | 1 | |a Methods in enzymology ; |v vol. 399 | |
| 504 | |a Includes bibliographical references and indexes. | ||
| 588 | 0 | |a Print version record. | |
| 520 | 3 | |a Ubiquitin and Protein Degradation, Part B will cover chemical biology, ubiquitin derivatives and ubiquitin-like proteins, deubiquitinating enzymes, proteomics as well as techniques to monitor protein degradation. The chapters are highly methodological and focus on application of techniques. *Second part of the Ubiquitin and Protein Degration series *Topics include: E1 Enzymes, E2 Enzymes, E3 Enzymes, Proteasomes, and Isopeptidases. | |
| 505 | 0 | |a 1. Chemical and Genetic Strategies for Manipulating Polyubiquitin Chain Structure -- SARA VOLK, MIN WANG, AND CECILE M. PICKART -- 2. Controlled Synthesis of Polyubiquitin Chains -- CECILE M. PICKART AND SHAHRI RAASI -- 3. Derivitization of the C-Terminus of Ubiquitin and Ubiquitin-Like Proteins Using Intein Chemistry: Methods and Uses -- KEITH D. WILKINSON, TUDEVIIN GAN-ERDENE, AND NAGAMALLESWARI KOLLI -- 4. Preparation, Characterization, and Use of Tagged Ubiquitins -- JUDY CALLIS AND RICHARD LING -- 5. Knocking out Ubiquitin Proteasome System Function In Vivo and In Vitro with Genetically Encodable Tandem Ubiquitin -- Y. SAEKI, E. ISONO, M. SHIMADA, H. KAWAHARA, H. YOKOSAWA, AND A. TOH-E -- 6. Production of Antipolyubiquitin Monoclonal Antibodies and Their Use for Characterization and Isolation of Polyubiquitinated Proteins -- MASAHIRO FUJMURO AND HIDEYOSHI YOKOSAWA -- 7. Application of Ubiquitin Immunohistochemistry to Diagnosis of Disease -- JAMES LOWE, NEIL HAND, AND JOHN MAYER -- 8. Mechanism-Based Proteomics Tools Based on Ubiquitin and Ubiquitin-Like Proteins: Crystallography, Activity Profiling, and Protease Identification -- PAUL J. GALARDY, HIDDE L. PLOEGH, AND HUIB OVAA -- 9. Identification and Characterization of Modular Domains That Bind Ubiquitin -- MICHAEL FRENCH, KURT SWANSON, SUSAN C. SHIN, ISHWAR RADHAKRISHNAN, AND LINDA HICKE -- 10. Analysis of Ubiquitin Chain-Binding Proteins by Two-Hybrid Methods -- JENNIFER APODACA, JUNGMI AHN, IKJIN KIM, AND HAI RAO -- 11. Quantifying Protein Protein Interactions in the Ubiquitin Pathway by Surface Plasmon Resonance -- RASMUS HARTMANN-PETERSON AND COLIN GORDON -- 12. Using NMR Spectroscopy to Monitor Ubiquitin Chain Conformation and Interactions with Ubiquitin-Binding Domains -- RANJANI VARADAN, MICHAEL ASSFALG, AND DAVID FUSHMAN -- 13. Analysis of Ubquitin-Dependent Protein Sorting Within the Endocytic Pathway in Saccharomyces cerevisiae -- DAVID J. KATZMANN AND BEVERLY WENDLAND -- 14. Preparation of Ubiquitinated Substrates by the PY Motif-Insertion Method for Monitoring 26S Proteasome Activity -- Y. SAEKI, E. ISONO, AND A. TOH-E -- 15. Large- and Small-Scale Purification of Mammalian 26S Proteasomes -- YUKO HIRANO, SHIGEO MURATA, AND KEIJI TANAKA -- 16. Is This Protein Ubiquitinated? -- PETER KAISER AND CHRISTIAN TAGWERKER -- 17. Experimental Tests to Definitively Determine Ubiquitylation of a Substrate -- JOANNA BLOOM AND MICHELE PAGANO -- 18. Identification of Ubiquitination Sites and Determination of Ubiquitin-Chain Architectures by Mass Spectrometry -- PETER KAISER AND JAMES WOHLSCHLEGEL -- 19. Mapping of Ubiquitination Sites on Target Proteins -- SHIGETSUGU HATAKEYAMA, MASAKI MATSUMOTO, AND KEIICHI I. NAKAYAMA -- 20. Identification of Substrates for F-Box Proteins -- JIANPING JIN, XIAOLU L. ANG, TAKAHIRO SHIROGANE, AND J. WADE HARPER -- 21. Fusion-Based Strategies to Identify Genes Involved in Degradations of a Specific Substrate -- RANDOLPH Y. HAMPTON -- 22. Bi-Substrate Kinetic Analysis of an E3-Ligase-Dependent Ubiquitylation Reaction -- DAVID C. SWINNEY, MICHAEL J. ROSE, AMY Y. MAK, INA LEE, LILIANA SCARAFIA, AND YI-ZHENG XU -- 23. Screening of Tissue Microarrays for Ubiquitin Proteasome System Components in Tumors -- NORMAN L. LEHMAN, MATT VAN DE RIJN, AND PETER K. JACKSON -- 24. Structure-Based Approaches to Create New E2-E3 Enzyme Pairs -- G. SEBASTIAN WINKLER AND H. TH. MARC TIMMERS -- 25. Proteomic Analysis of Ubiquitin Conjugates in Yeast -- JUNMIN PENG AND DONGMEI CHENG -- 26. Two-Step Affinity Purification of Multiubiquitylated Proteins from Saccharomyces cerevisiae -- THIBAULT MAYOR AND RAYMOND J. DESHAIES -- 27. Identification of SUMO-Protein Conjugates -- MEIK SACHER, BORIS PFANDER, AND STEFAN JENTSCH -- 28. Identification of Ubiquitin Ligase Substrates by In Vitro Expression Cloning -- NAGI G. AYAD, SUSANNAH RANKIN, DANNY OOI, MICHAEL RAPE, AND MARC W. KIRSCHNER -- 29. In Vitro Screening for Substrates of the N-End Rule-Dependent Ubiquitylation -- ILIA V. DAVYDOV, JOHN H. KENTEN, YASSAMIN J. SAFIRAN, STEFANIE NELSON, RYAN SWENERTON, PANKAJ OBEROI, AND HANS A. BIEBUYCK -- 30. Genome-Wide Surveys for Phosphorylation-Dependent Substrates of SCF Ubiquitin Ligases -- XIAOJING TANG, STEPHEN ORLICKY, QINGQUAN LIU, ANDREW WILLEMS, FRANK SICHERI, AND MIKE TYERS -- 31. Yeast Genomics in the Elucidation of Endoplasmic Reticulum (ER) Quality Control and Associated Protein Degradation (ERQD) -- ANTJE SCHAFER AND DIETER H. WOLF -- 32. Mechanism-Based Proteomics Tools Based on Ubiquitin and Ubiquitin-Like Proteins: Synthesis of Active-Site Directed Probes -- HUIB OVAA, PAUL J. GALARDY, AND HIDDE L. PLOEGH -- 33. Application and Analysis of the GFP Family of Ubiquitin-Proteasome System Reporters -- NEIL F. BENCE, ERIC J. BENNETT, AND RON R. KOPITO -- 34. Monitoring of Ubiquitin-Dependent Proteolysis with Green Fluorescent Protein Substrates -- VICTORIA MENENDEZ-BENITO, STIJN HEESSEN, AND NICO P. DANTUMA -- 35. Monitoring Proteasome Activity In Cellulo and in Living Animals by Bioluminescent Imaging: Technical Considerations for Design and Use of Genetically Encoded Reporters -- SHIMON GROSS AND DAVID PIWNICA-WORMS -- 36. Bioluminescent Imaging of Ubiquitin Ligase Activity: Measuring Cdk2 Activity In Vivo Through Changes in p27 Turnover -- GUO-JUN ZHANG AND WILLAM G. KAELIN, JR. -- 37. Monitoring the Distribution and Dynamics of Proteasomes in Living Cells -- TOM A.M. GROOTHUIS AND ERIC A.J. REITS -- 38. Identifying Small Molecules Inhibitors of the Ubiquitin-Proteasome Pathway in Xenopus Egg Extracts -- ADRIAN SALIC AND RANDALL W. KING -- 39. Development and Characterization of Proteasome Inhibitors -- KYUNG BO KIM, FABIANA N. FONSECA, AND CRAIG M. CREWS -- 40. Screening for Selective Small Molecule Inhibitors of the Proteasome Using Activity-Based Probes -- MATTHEW BOGYO -- 41. Development of E3-Substract (MDM2-p53)-Binding Inhibitors: Structural Aspects -- DAVID C. FRY, BRADFORD GRAVES, AND LYUBOMIR T. VASSILEV -- 42. Druggability of SCF Ubiquitin Ligase-Protein Interfaces -- TIMOTHY CARDOZO AND RUBEN ABAGYAN -- 43. Overview on Approaches for Screening for Ubiquitin Ligase Inhibitors -- YI SUN -- 44. A Homogeneous FRET Assay System for Multiubiquitin Chain Assembly and Disassembly -- TARIKERE L. GURURAJ, TODD R. PRAY, RAYMOND LOWE, GUOQIANG DONG, JIANING HUANG, SARKIZ DANIEL-ISSAKANI, AND DONALD G. PAYAN -- 45. Assays for High-Throughput Screening of E2 and E3 Ubiquitin Ligases -- JOHN H. KENTEN, ILIA V. DAVYDOV, YASSAMIN J. SAFIRAN, DAVID H. STEWART, PANKAJ OBEROI, AND HANS A. BIEBUYCK -- 46. Quantitative Assays for Mdm2 Ubiquitin Ligase Activity and Other Ubiquitin-Utilizing Enzymes for Inhibitor Discovery -- KURT R. AUGER, ROBERT A. COPELAND, AND ZHIHONG LAI -- 47. High-Throughput Screening for Inhibitors of the Cks1-Skp2 Interaction -- KUO-SEN HUANG AND LYUBOMIR T. VASSILEV -- 48. In Vitro SCFb-Trcp1-Mediated IKBa Ubiquitination Assay for High-Throughput Screen -- SHUICHAN Xu, PALKA PATEL, MAHAN ABBASIAN, DAVID GIEGEL, WEILIN XIE, FRANK MERCURIO, AND SARAH COX -- 49. High-Throughput Screening for Inhibitors of the E3 Ubiquitin Ligase APC -- JIANING HUANG, JULIE SHEUNG, GUOQIANG DONG, CHRISTINA COQUILLA, SARKIZ DANIEL-ISSAKANI, AND DONALD G. PAYAN -- 50. The Split-Ubiquitin Sensor: Measuring Interactions and Conformational Alterations of Proteins In Vivo -- CHRISTOPH REICHEL AND NILS JOHNSSON -- 51. Ubiquitin Fusion Technique and Related Methods -- ALEXANDER VARSHAVSKY -- 52. Heat-Inducible Degron and the Making of Codintional Mutants -- R. JURGEN DOHMEN AND ALEXANDER VARSHAVSKY -- 53. Ectopic Targeting of Substrates to the Ubiquitin Pathway -- JIANXUAN ZHANG AND PENGBO ZHOU -- 54. Chimeric Molecules to Target Proteins for Ubiquitination and Degradation -- KATHLEEN M. SAKAMOTO. | |
| 650 | 0 | |a Ubiquitin. | |
| 650 | 0 | |a Proteolysis. | |
| 650 | 0 | |a Enzymatic analysis. | |
| 650 | 0 | |a Proteins |x Metabolism. | |
| 650 | 0 | |a Proteolytic enzymes. | |
| 650 | 0 | 2 | |a Proteins |x analysis |0 (DNLM)D011506Q000032 |
| 650 | 0 | 2 | |a Proteins |x metabolism |0 (DNLM)D011506Q000378 |
| 650 | 0 | 2 | |a Ubiquitins |x analysis |0 (DNLM)D014452Q000032 |
| 650 | 0 | 2 | |a Ubiquitins |x physiology |0 (DNLM)D014452Q000502 |
| 650 | 0 | 2 | |a Ubiquitins |x therapeutic use |0 (DNLM)D014452Q000627 |
| 650 | 2 | |a Ubiquitins |0 (DNLM)D014452 | |
| 650 | 2 | |a Proteolysis |0 (DNLM)D059748 | |
| 650 | 2 | |a Peptide Hydrolases |0 (DNLM)D010447 | |
| 650 | 6 | |a Ubiquitine. |0 (CaQQLa)201-0267513 | |
| 650 | 6 | |a Prot�eolyse. |0 (CaQQLa)000293714 | |
| 650 | 6 | |a Analyse enzymatique. |0 (CaQQLa)201-0033454 | |
| 650 | 6 | |a Prot�eines |x M�etabolisme. |0 (CaQQLa)201-0031404 | |
| 650 | 6 | |a Enzymes prot�eolytiques. |0 (CaQQLa)201-0055592 | |
| 650 | 7 | |a Proteolysis |2 fast |0 (OCoLC)fst01930489 | |
| 650 | 7 | |a Enzymatic analysis. |2 fast |0 (OCoLC)fst00913593 | |
| 650 | 7 | |a Proteins |x Metabolism. |2 fast |0 (OCoLC)fst01079741 | |
| 650 | 7 | |a Proteolytic enzymes. |2 fast |0 (OCoLC)fst01079783 | |
| 650 | 7 | |a Ubiquitin. |2 fast |0 (OCoLC)fst01160282 | |
| 700 | 1 | |a Deshaies, Raymond Joseph, |d 1961- |e editor. | |
| 776 | |z 0-12-182804-2 | ||
| 830 | 0 | |a Methods in enzymology ; |v vol. 399. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780121828042 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00766879/399 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00766879/399 |z Texto completo |