Cargando…
G protein coupled receptors. Modeling, activation, interactions and virtual screening /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, Calif. :
Academic,
2013.
|
| Colección: | Methods in enzymology ;
v. 522. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
| LEADER | 00000cam a2200000Ii 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn828711117 | ||
| 003 | OCoLC | ||
| 005 | 20231117044832.0 | ||
| 006 | m o d | ||
| 007 | cr mnu---uuaaa | ||
| 008 | 130218s2013 caua ob 001 0 eng | ||
| 040 | |a AU@ |b eng |e pn |c AU@ |d E7B |d OCLCO |d OCLCQ |d CUS |d UIU |d OPELS |d OCLCF |d KUK |d OCLCQ |d AZS |d OCLCQ |d OCLCA |d CASUM |d OCLCO |d MERER |d OCLCO |d OCLCQ |d OCLCA |d ANS |d OCLCO |d OCLCA |d YOU |d SOI |d OCLCO |d LEAUB |d OCLCQ |d OL$ |d OCLCA |d OCLCO |d OCLCQ |d OCLCO | ||
| 020 | |a 9780124078659 | ||
| 020 | |a 0124078656 | ||
| 035 | |a (OCoLC)828711117 | ||
| 050 | 4 | |a QP552.G16 .G384 2013 | |
| 082 | 0 | 4 | |a 572/.696 |2 23 |
| 245 | 0 | 0 | |a G protein coupled receptors. |p Modeling, activation, interactions and virtual screening / |c edited by P. Michael Conn. |
| 246 | 3 | |a Modeling, activation, interactions and virtual screening | |
| 260 | |a San Diego, Calif. : |b Academic, |c 2013. | ||
| 300 | |a 1 online resource (lvi, 472 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a data file |2 rda | ||
| 490 | 1 | |a Methods in enzymology, |x 0076-6879 ; |v v. 522 | |
| 504 | |a Includes bibliographical references and indexes. | ||
| 505 | 0 | |a The protein local optimization program and g-protein-coupled receptors:loop restoration and applications to homology modeling -- Modeling active GPCR conformations -- Molecular modeling of adenosine receptors -- Predicting g-protein-coupled receptors families using differet physiochemical properties and pseudo amino acid composition -- Computational design and experimental characterization of GPCR segment models -- G-protein-coupled receptor interaction with small GTPases -- Quantification of receptor tyrosine kinase activiation and transactivation by G-protein-coupled receptors using spatial intensity distribution analysis (SplDA) -- NMR modeling for detection of small molecule binding to RGS4 -- Group II activators of g-protein signaling: monitoring the interaction of G[alpha] with G-protein motif in the intact cell -- Homogenous time-resolved fluorescence assay to probe folded G protein-coupled receptors -- cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors -- Rhodospin-lipid intereactions studied by NMR -- Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity -- Application of Monte Carlo-based receptor ensemble docking to virtual screening for GPCR ligands -- From heptahelical bundle to hits from the haystack: structure-based virtual screening for GPCR ligands -- Kinetics and dynamics in the G protein-coupled receptor signaling cascade -- Magic angle spinning nuclear magnetic resonance spectroscopy fo G protein-coupled receptors -- Posttranslation modification of G protein-coupled receptor in relationship to biased agonism -- Protein S-nitrosylation measurement. | |
| 650 | 0 | |a Cell receptors |x Structure-activity relationships. | |
| 650 | 0 | |a G proteins |x Receptors. | |
| 650 | 1 | 2 | |a Receptors, G-Protein-Coupled |x analysis |0 (DNLM)D043562Q000032 |
| 650 | 1 | 2 | |a Receptors, G-Protein-Coupled |x physiology |0 (DNLM)D043562Q000502 |
| 650 | 2 | 2 | |a Magnetic Resonance Spectroscopy |0 (DNLM)D009682 |
| 650 | 6 | |a R�ecepteurs cellulaires |x Relations structure-activit�e. |0 (CaQQLa)201-0228604 | |
| 650 | 6 | |a Prot�eines G |0 (CaQQLa)201-0203891 |x R�ecepteurs. |0 (CaQQLa)201-0375415 | |
| 650 | 7 | |a Cell receptors |x Structure-activity relationships |2 fast |0 (OCoLC)fst00850232 | |
| 650 | 7 | |a G proteins |x Receptors |2 fast |0 (OCoLC)fst00936832 | |
| 655 | 4 | |a Internet Resources. | |
| 700 | 1 | |a Conn, P. Michael. | |
| 830 | 0 | |a Methods in enzymology ; |v v. 522. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780124078659 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00766879/522 |z Texto completo |