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Heart development /
The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in hear...
| Call Number: | Libro Electrónico |
|---|---|
| Other Authors: | |
| Format: | Electronic eBook |
| Language: | Inglés |
| Published: |
San Diego, Calif. :
Academic Press,
2012.
|
| Edition: | 1st ed. |
| Series: | Current topics in developmental biology ;
v. 100. |
| Subjects: | |
| Online Access: | Texto completo |
Table of Contents:
- Front Cover; Heart Development; Copyright; Contents; Contributors; Preface; Chapter 1: Life Before Nkx2.5: Cardiovascular Progenitor Cells: Embryonic Origins and Development; 1 Introduction; 2 Early Heart Development: Is It as Simple as Location, Location, Location?; 3 CPCs: The Building Blocks of the Heart; 4 CPC Determination: The Quest for ""Cardiod""; 5 Signaling Pathways and CPC Fate; 6 A Moving Story: Early CPC Migration and Fate; 7 Changing the Program: CPC Relationship to Reprogramming and Transdifferentiation; 8 Conclusions: Future Questions and Possible Applications; Acknowledgments
- 6 The Second Heart Field in Vertebrate Evolution7 The Second Heart Field as Part of a Cardiocraniofacial Developmental Field; 8 Perspectives; Acknowledgments; References; Chapter 3: An Unauthorized Biography of the Second Heart Field and a Pioneer/Scaffold Model for Cardiac Development; 1 Introduction; 2 Subpharyngeal Cardiac Precursors; 2.1 Using soft words and hard arguments; 2.1.1 Strong; 2.1.2 Light; 3 Models of Cardiac Development; 3.1 Mosaic, regulative or a patterned mosaic?; 3.2 Retrospective fate mapping highlights the intrinsic unity of the cardiac progenitor population
- 4 A Historical Account of the SHF Concept4.1 Is the SHF a novel cardiac progenitor domain?; 4.2 Is the SHF a cardiac progenitor region defined on the basis of specific gene expression?; 4.3 Is the SHF a progenitor population defined by expression of specific markers?; 5 Evolution of Isl Expression in Cardiac Development; 5.1 Origins of Isl-1-expression in cardiac progenitors: Rewinding, not rewriting, the tape of cardiac evolution...; 5.2 A comparative analysis of Isl expression in vertebrate chambered heart development; 5.2.1 Mice; 5.2.2 Chicken; 5.2.3 Frogs; 5.2.4 Zebrafish; 5.2.5 Lampreys
- 5.3 A comparative analysis of Isl expression during the ontogenesis of invertebrate circulatory pumps5.3.1 Ascidian tunicates; 5.3.2 The cephalochordate amphioxus; 5.3.3 Drosophila; 5.4 Origins of Isl-1-expression in cardiac progenitors: A synthesis; 6 Subpharyngeal Cardiac Precursors and Segmental Models of Myocardial Cell Regionalization; 6.1 The axial organization of cardiac segments versus subpharyngeal cardiac precursors: Are these contradictory?...; 6.2 The AP organization of cardiac segments is questioned; 6.3 Do cardiac fate maps reveal an AP organization of cardiac segments?