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Experimental and comparative toxicology /
Experimental and Comparative Toxicology, Volume 31 aims to explore some of the potentially important and crucial areas in experimental toxicology. The book discusses tumor promoters and genotoxic chemicals in short-term testing for carcinogenicity, as well as the significance of preneoplastic liver...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Orlando :
Academic,
1987.
|
| Colección: | Advances in veterinary science and comparative medicine ;
v. 31. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 035 | |a (OCoLC)762670812 |z (OCoLC)896795753 |z (OCoLC)1162591658 | ||
| 050 | 4 | |a SF745 |b .A39 v.31 | |
| 060 | 4 | |a W1 |b AD885 v.31 1987 | |
| 060 | 4 | |a QV 602 |b E96 1987 | |
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| 082 | 0 | 4 | |a 636.08959 |
| 245 | 0 | 0 | |a Experimental and comparative toxicology / |c guest editor, Andr�e G. Rico. |
| 260 | |a Orlando : |b Academic, |c 1987. | ||
| 300 | |a 1 online resource (xiv, 204 pages) : |b illustrations, portrait | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Advances in veterinary science and comparative medicine ; |v v. 31 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; Experimental and Comparative Toxicology; Copyright Page; Table of Contents; Preface; Chapter 1. Tumor Promotors and Genotoxic Chemicals in Short-Term Testing for Carcinogenicity; I. Introduction; II Complete and ""Incomplete"" Carcinogens; III. Acute and Chronic Toxicity; IV. New Testing Strategies; V. Conclusions; References; Chapter 2. The Significance of Preneoplastic Liver Lesions in Experimental Animals; I. Introduction; II. Significance of Preneoplastic Lesions; III. Characteristics of Altered Foci; IV. Induction of Altered Foci as a Means of Detecting Carcinogens. | |
| 505 | 8 | |a v. Enhancement of Altered Foci as a Means of Identifying Neoplasm-Promoting AgentsVI. Inhibition of Altered Foci as a Means of Identifying Anticarcinogens; VII. Conclusions; References; Chapter 3. Liver Tumors in Rodents: Extrapolation to Man; I. Introduction; II. Different Kinds of Liver Tumors; III. Etiological Factors for Hepatic Neoplasia in Man and the Availability of Animal Models; IV. Mortality from Primary Liver Cancer in England and Wales; V. Factors Other Than Test Chemicals Which Influence the Risk of Hepatic Neoplasia in Laboratory Rodents. | |
| 505 | 8 | |a VI. The Significance of Enzyme-Altered Foci in the Pathogenesis of Hepatocellular NeoplasiaVII. The Prediction of Hepatocarcinogenic Risk for Man; VIII. Summary; References; Chapter 4. Neurobehavioral Toxicology: An Overview; I. Introduction; II. Neurobehavioral Toxicology: A Historical Perspective; III. Methods in Neurobehavioral Toxicology; IV. Corroborating Tests; V. Neurobehavioral Assessment of Neurotoxins: Past and Present; VI. Topics for Future Research; References; Chapter 5. Immunotoxicology; I. Introduction; II. Brief Anatomical and Physiological Considerations. | |
| 505 | 8 | |6 880-01 |a Chapter 8. Predictive Value of Ocular Irritation TestsI. Introduction; II. Tests Presently Used; III. Are Tests Presently Used Predictive?; IV. Can We Improve the Predictivity of the Tests?; V. Can We Develop Alternative Methods to the Use of Animals?; VI. Conclusions; References; Index. | |
| 520 | |a Experimental and Comparative Toxicology, Volume 31 aims to explore some of the potentially important and crucial areas in experimental toxicology. The book discusses tumor promoters and genotoxic chemicals in short-term testing for carcinogenicity, as well as the significance of preneoplastic liver lesions in experimental animals. The text also describes the factors known to be associated with increased risk of liver neoplasia as a human disease, and the extent to which it is known that the same factors have a similar effect in laboratory animals. Neurobehavioral toxicology; immunotoxicology. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Toxicology. | |
| 650 | 0 | |a Toxicology, Experimental. | |
| 650 | 0 | |a Xenobiotics. | |
| 650 | 0 | |a Oncology, Experimental. | |
| 650 | 2 | |a Carcinogens |x toxicity |0 (DNLM)D002273Q000633 | |
| 650 | 2 | |a Mutagenicity Tests |x methods |0 (DNLM)D009152Q000379 | |
| 650 | 2 | |a Neoplasms, Experimental |0 (DNLM)D009374 | |
| 650 | 2 | |a Toxicology |x methods |0 (DNLM)D014116Q000379 | |
| 650 | 2 | |a Toxicology |0 (DNLM)D014116 | |
| 650 | 2 | |a Xenobiotics |0 (DNLM)D015262 | |
| 650 | 6 | |a Toxicologie. |0 (CaQQLa)201-0054329 | |
| 650 | 6 | |a Toxicologie exp�erimentale. |0 (CaQQLa)201-0072443 | |
| 650 | 6 | |a X�enobiotiques. |0 (CaQQLa)201-0113162 | |
| 650 | 6 | |a Canc�erologie exp�erimentale. |0 (CaQQLa)201-0049886 | |
| 650 | 7 | |a toxicology. |2 aat |0 (CStmoGRI)aat300251568 | |
| 650 | 7 | |a TECHNOLOGY & ENGINEERING |x Agriculture |x Animal Husbandry. |2 bisacsh | |
| 650 | 7 | |a Oncology, Experimental |2 fast |0 (OCoLC)fst01045747 | |
| 650 | 7 | |a Toxicology |2 fast |0 (OCoLC)fst01153364 | |
| 650 | 7 | |a Toxicology, Experimental |2 fast |0 (OCoLC)fst01153392 | |
| 650 | 7 | |a Xenobiotics |2 fast |0 (OCoLC)fst01181971 | |
| 700 | 1 | |a Rico, Andr�e G. | |
| 776 | 0 | 8 | |i Print version: |t Experimental and comparative toxicology. |d Orlando : Academic, 1987 |w (OCoLC)18782036 |
| 830 | 0 | |a Advances in veterinary science and comparative medicine ; |v v. 31. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780120392315 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00653519/31 |z Texto completo |
| 880 | 8 | |6 505-01/(S |a III. Proposed Models for Immunotoxicity AssessmentIV. Conclusion; References; Chapter 6. The Endocrine System as the Target in Experimental Toxicology; I. Introduction; II. No-Hormonal-Effect Level; III. Practical Considerations; IV. Applied Techniques; V. Experimental Practice; References; Chapter 7. Uses of γ-Glutamyltransferase in Experimental Toxicology; I. Introduction; IL Distribution of the Enzyme; III. Hepatic Induction and Hepatic Disturbances; IV. GGT and Experimental Carcinogenesis; V. Urine GGT in Experimental Kidney Toxicity; VI. Conclusion; References. | |