Cargando…
International review of neurobiology. Volume 36 /
Published since 1959, this serial presents in-depth reviews on key topics in neuroscience, from molecules to behavior. The serial stays keenly attuned to recent developments in the field through the contributions offirst-class experts. Neuroscientists as well as clinicians, psychologists, physiologi...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
1994.
|
| Colección: | International review of neurobiology ;
36. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; International Review of Neurobiology, Volume 36; Copyright Page; Contents; Chapter 1. Ca2+, N-Methyl-D-aspartate Receptors, and AIDS-Related Neuronal Injury; I. Introduction; II. Neuronal Loss in the CNS of AIDS Patients; III. gpl20-Induced Neuronal Injury Is Ameliorated by Calcium Channel Anotagonists; IV. Involvement of the NMDA Receptor in gpl20-Induced Neuronal Injury; V. Indirect Neuronal Injury Mediated by HIV-Infected or gp120-Stimulated Monocytic Cells; VI. Possible Involvement of Astrocytes, Oligodendrocytes, and Other HIV-1 Proteins in Neuronal Injury
- VII. Overstimulation of NMDA Receptors, a Final Common PathwayVIII. Development of Clinically Tolerated NMDA Antagonists for HIV-Related Neuronal Injury; IX. Excitatory Amino Acid Antagonist Treatments on the Horizon; X. Conclusion; References; Chapter 2. Processing of Alzheimer A�-Amyloid Precursor Protein: Cell Biology, Regulation, and Role in Alzheimer Disease; I. Introduction; II. Alzheimer Disease Is Associated with an Intracranial Amyloidosis; III. APP Structure Gives Clues to Some of Its Functions; IV. APP Is Processed via Several Distinct Enzymatic and Subcellular Pathways
- V. "Alternative" Pathways of APP Metabolism Provide Clues to the Source of A�-AmyloidVI. A�-Amyloid Is a Normal Constituent of Body Fluids and the Conditioned Medium of Cultured Cells; VII. Evidence Suggests the Existence of an Enzyme, �-Secretase, That Cleaves APP at the Amino Terminus of the A�-Amyloid Domain; VIII. APP Mutations in Familial Cerebral Amyloidoses Occur within or near the A�-Amyloid Domain, Segregate with Disease in Affected Kindreds, and Yield APP Molecules That Display Some Proamyloidogenic Properties
- IX. Signal Transduction via Protein Phosphorylation Regulates the Relative Utilization of APP Processing PathwaysX. Beyond A�-Amyloid: Other Molecular Factors in Amyloidogenesis and Factors Differentiating Aging-Related Cerebral Amyloidosis from Alzheimer Disease; References; Chapter 3. Molecular Neurobiology of the GABAA Receptor; I. Introduction; II. Pharmacology of the GABAA Receptor; III. Biochemistry; IV. Molecular Cloning of Receptor Subunits; V. Characterization of the Receptor Family; VI. The Future; Reference; Chapter 4. The Pharmacology and Function of Central GABAB Receptors
- I. IntroductionII. Pharmacology of GABAB Receptors; III. Properties of GABAB Receptors; IV. Function of GABAB Receptors; V. Summary and Conclusions; References; Chapter 5.The Role of the Amygdala in Emotional Learning; I. Introduction; II. Morphology; III. Electrophysiology; IV. Anatomical Connections between the Amygdala and Brain Areas Involved in Fear and Anxiety; V. Elicitation of Fear by Electrical or Chemical Stimulation of the Amygdagdala; VI. Effects of Amygdala Lesions on Conditioned Fear; VII. Effects of Amygdala Lesions on Unconditioned Fear