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Drug-drug interactions : scientific and regulatory perspectives /

Drug-Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug-drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governme...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Li, A. P.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, Calif. : Academic Press, �1997.
Colección:Advances in pharmacology ; v. 43.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Drug-drug interactions :  |b scientific and regulatory perspectives /  |c edited by Albert P. Li. 
260 |a San Diego, Calif. :  |b Academic Press,  |c �1997. 
300 |a 1 online resource (xviii, 304 pages) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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490 1 |a Advances in pharmacology ;  |v v. 43 
520 |a Drug-Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug-drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug-drug interactions, the prediction of drug-drug interaction potential of new drugs, and the avoidance of clinically significant drug-drug interaction in patients. Key Features * Provides useful references on the science of drug-drug interactions * Describes in a basic and comprehensive manner drug-drug interactions from the mechanistic viewpoint * Contains original data from academic and industrial laboratories * Presents an overview of regulatory agency positions. 
504 |a Includes bibliographical references and index. 
505 0 0 |t Overview : pharmacokinetic drug-drug interactions /  |r Albert P. Li and Malle Jurima-Romet --  |t Role of cytochrome P450 enzymes in drug-drug interactions /  |r F. Peter Guengerich --  |t Liver as a target for chemical-chemical interactions /  |r John-Michael Sauer [and others] --  |t Application of human liver microsomes in metabolism-based drug-drug interactions : in vitro-in vivo correlations and the Abbott Laboratories experience /  |r A. David Rodrigues and Shekman L. Wong --  |t Primary hepatocyte cultures as an in vitro experimental model for the evaluation of pharmacokinetic drug-drug interactions /  |r Albert P. Li --  |t Liver slices as a model in drug metabolism /  |r James L. Ferrero and Klaus Brendel --  |t Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions /  |r Charles L. Crespi and Bruce W. Penman. 
505 0 0 |t Pharmacokinetics of drug interactions /  |r Gregory L. Kedderis --  |t Experimental models for evaluating enzyme induction potential of new drug candidates in animals and humans and a strategy for their use /  |r Thomas N. Thompson --  |t Metabolic drug-drug interactions : perspective from FDA medical and clinical pharmacology reviewers /  |r John Dikran Balian and Atiqur Rahman --  |t Drug interactions : perspectives of the Canadian Drugs Directorate /  |r Malle Jurima-Romet --  |t Overview of experimental approaches for study of drug metabolism and drug-drug interactions /  |r Frank J. Gonzalez. 
588 0 |a Print version record. 
546 |a English. 
650 0 |a Drug interactions. 
650 0 |a Pharmacology. 
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650 6 |a Pharmacologie.  |0 (CaQQLa)201-0007219 
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700 1 |a Li, A. P. 
776 0 8 |i Print version:  |t Drug-drug interactions.  |d San Diego, Calif. : Academic Press, �1997  |z 0120329441  |w (OCoLC)37781352 
830 0 |a Advances in pharmacology ;  |v v. 43. 
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