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Advances in organ biology. Volume 6, Myocardial preservation and cellular adaptation /
Living organisms exhibit specific responses when confronted with sudden changes in their environmental conditions. The ability of the cells to acclimate to their new environment is the integral driving force for adaptive modification of the cells. Such adaptation involves a number of cellular and bi...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Greenwich, CT :
JAI Press,
�1998.
|
| Colección: | Advances in organ biology ;
6. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 082 | 0 | 4 | |a 612.1/7 |2 23 |
| 245 | 0 | 0 | |a Advances in organ biology. |n Volume 6, |p Myocardial preservation and cellular adaptation / |c guest editor Dipak K. Das. |
| 260 | |a Greenwich, CT : |b JAI Press, |c �1998. | ||
| 300 | |a 1 online resource (xi, 275 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Advances in organ biology ; |v 6 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a Living organisms exhibit specific responses when confronted with sudden changes in their environmental conditions. The ability of the cells to acclimate to their new environment is the integral driving force for adaptive modification of the cells. Such adaptation involves a number of cellular and biochemical alteration including metabolic homeostasis and reprogramming of gene expression. Changes in metabolic pathways are generally short-lived and reversible, while the consequences of gene expression are a long-term process and may lead to permanent alternation in the pattern of adaptive responses. The heart possesses remarkable ability to adapt itself against any stressful situation by increasing resistance to the adverse consequences. Stress composes the foundation of many degenerative heart diseases including atherosclerosis, spasm, thrombosis, cardiomyopathy, and congestive heart failure. Based on the concept that excessive stress may play a crucial role in the pathogenesis of ischemic heart disease, attempts were made to design methods for preventing of myocardial injury. Creation of stress reactions by repeated ischemia and reperfusion or subjecting the hearts to heat or oxidative stress enables them to meet the future stress challenge. Repeated stress exposures adapt the heart to withstand more severe stress reactions probably by upregulating the cellular defense and direct accumulation of intracellular mediators, which presumably constitute the material basis of increased adaptation to stress. Thus, the powerful cardioprotective effect of adaptation is likely to originate at the cellular and molecular levels that compose fundamental processes in the prophylaxis of such diseases. Volume six of the Advances in Organ Biology series contains state-of-the-art reviews on myocardial preservation and cellular adaptation from the leading authorities in this subject. | ||
| 505 | 0 | |a Front Cover; Advances in Organ Biology: Myocardial Preservation and Cellular Adaptation; Copyright Page; CONTENTS; LIST OF CONTRIBUTORS; PREFACE; CHAPTER 1. PRECONDITIONING INDUCES BOTH IMMEDIATE AND DELAYED PROTECTION AGAINST ARRHYTHMIAS RESULTING FROM ISCHEMIA AND REPERFUSION; CHAPTER 2. MYOCARDIAL PROTECTION BY BRIEF ISCHEMIC AND NONISCHEMIC STRESS; CHAPTER 3. CARDIAC ADAPTATION TO CHRONIC HYPOXIA; CHAPTER 4. ANALYSIS OF ALTERED GENE EXPRESSION DURING ISCHEMlC PRECONDITIONING; CHAPTER 5. MYOCARDIAL PRECONDITIONING VIA ATP-SENSITIVE POTASSIUM CHANNELS: INTERACTIONS WITH ADENOSINE | |
| 505 | 8 | |a CHAPTER 6. ISCHEMIC PRECONDITIONING: ROLE OF MULTIPLE KINASES IN SIGNAL AMPLIFICATION AND MODULATIONCHAPTER 7. EARLY AND LATE PRECONDITIONING AGAINST MYOCARDIAL STUNNING: PATHOGENESIS AND PATHOPHYSIOLOGY; CHAPTER 8. CHANGES IN CARDIAC ENERGETICS DURING PRECONDITIONING AND ADAPTATION; CHAPTER 9. MOLECULAR ADAPTATION OF TRANSCRIPTIONAL APPARATUS IN CARDIAC HYPERTROPHY AND EMBRYONIC DEVELOPMENT; CHAPTER 10. SIGNAL DIVERGENCE AND CONVERGENCE IN CARDIAC ADAPTATION; CHAPTER 11. THE ROLE OF ATP-SENSITIVE POTASSIUM CHANNELS IN MYOCARDIAL ISCHEMIC STRESS | |
| 505 | 8 | |a CHAPTER 12. DELAYED PRECONDlTlONING: MECHANISMS OF ENDOGENOUS AND PHARMACOLOGIC INDUCTION OF THIS ADAPTIVE RESPONSE TO ISCHEMIACHAPTER 13. ADAPTATION OF CELLULAR THERMOGENIC REACTIONS; CHAPTER 14. FROM RAYNAUD'S PHENOMENON TO SYSTEMIC SCLEROSIS (SCLERODERMA): LACK OR EXHAUSTION OF ADAPTATION?; CHAPTER 15. MOLECULAR ADAPTATION TO TOXIC CHEMICALS AND DRUGS; INDEX | |
| 546 | |a English. | ||
| 650 | 0 | |a Myocardium |x Pathophysiology. | |
| 650 | 0 | |a Myocardium |x Adaptation. | |
| 650 | 6 | |a Myocarde |0 (CaQQLa)201-0046117 |x Physiopathologie. |0 (CaQQLa)201-0379296 | |
| 650 | 6 | |a Myocarde |0 (CaQQLa)201-0046117 |x Adaptation. |0 (CaQQLa)201-0374431 | |
| 650 | 7 | |a Myocardium |x Adaptation |2 fast |0 (OCoLC)fst01031457 | |
| 650 | 7 | |a Myocardium |x Pathophysiology |2 fast |0 (OCoLC)fst01031463 | |
| 700 | 1 | |a Das, Dipak Kumar, |d 1946- | |
| 776 | 0 | 8 | |i Print version: |t Advances in organ biology. |d Greenwich, CT : JAI Press, �1998 |w (DLC) 97050026 |
| 830 | 0 | |a Advances in organ biology ; |v 6. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780762303915 |z Texto completo |