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100702s1990 enkf ob 101 0 eng d |
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|a OCLCE
|b eng
|e pn
|c OCLCE
|d OCLCQ
|d UIU
|d OCLCF
|d YDXCP
|d IDEBK
|d E7B
|d OCLCQ
|d UKAHL
|d VLY
|d LUN
|d UKQUB
|d OCLCQ
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|d OCLCQ
|d OCLCO
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019 |
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|a 608614011
|a 872652718
|a 1100878818
|a 1162414632
|a 1179424493
|a 1233319273
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|a 130648071X
|q (ebk)
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|a 9781306480710
|q (ebk)
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|a 9781483288246
|q (e-book)
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|a 1483288242
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|z 0121366707
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|z 9780121366704
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|a (OCoLC)645898291
|z (OCoLC)608614011
|z (OCoLC)872652718
|z (OCoLC)1100878818
|z (OCoLC)1162414632
|z (OCoLC)1179424493
|z (OCoLC)1233319273
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|a dlr
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|a QP517.C57
|b C45 1990
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|a 615.3
|2 20
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|a 44.42
|2 bcl
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|a Chirality in drug design and synthesis /
|c edited by C. Brown.
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260 |
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|b Academic,
|c �1990.
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300 |
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|a 1 online resource (xv, 243 pages, 4 unnumbered pages of plates)
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|3 Use copy
|f Restrictions unspecified
|2 star
|5 MiAaHDL
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|a Electronic reproduction.
|b [Place of publication not identified] :
|c HathiTrust Digital Library,
|d 2010.
|5 MiAaHDL
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|a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
|u http://purl.oclc.org/DLF/benchrepro0212
|5 MiAaHDL
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|a digitized
|c 2010
|h HathiTrust Digital Library
|l committed to preserve
|2 pda
|5 MiAaHDL
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|a Print version record.
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|a Includes bibliographical references and index.
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|a Front Cover; Dedication; Chirality in Drug Design and Synthesis; Copyright Page; Contributors; Foreword; Table of Contents; Introduction; Chapter 1. Chirality: Pharmacological Action and Drug Development; Introduction; 2 Terminology; 3 Enantioselectivity in pharmacological activity; 4 Enantioselectivity in pharmacodynamics resulting from differences in the pharmacokinetics of the enantiomers; 5 Conclusion; References; Chapter 2. Racemic Therapeutics-Problems all Along the Line; 1 Introduction; 2 Implications of chirality in bioactive agents; 3 Clinical pharmacology of racemic therapeutics
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|a 4 Ethical aspects of drug development, evaluation and use5 Non-information and disinformation in the field of chirality; 6 Racemates as drug combinations; 7 Perspectives; 8 Summary; References; Chapter 3. Chirality, Drug Metabolism and Action; 1 Introduction; 2 Stereochemistry and drug disposition; 3 Stereoselective metabolism and drug action; 4 Conclusions; References; Chapter 4. From Enzyme Mimics to Molecular Self-Assembly Processes; 1 Introduction; 2 A gift from nature; 3 Needs of enzyme mimics; 4 Serendipity yet again; 5 A chiral crown ether as a reagent
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|a 6 The same chiral crown ether as a catalyst7 Coordination through the second sphere; 8 Planned molecular self-assembly; 9 From host-guest chemistry to molecular assemblies; 10 Structure-directed synthesis; 11 The future; Acknowledgements; References; Chapter 5. Modelling of Drug-Receptor Interactions: Stereoselectivity of 5-Hydroxytryptamine and Dopamine Receptors in the Brain; 1 Introduction; 2 Interactions between L-ZGP and 8-OH DPAT; 3 Modelling of drug-receptor interactions; 4 DA D2-receptor agonists and antagonists; 5 5-HT1A-receptor agonists and antagonists; Acknowledgements; References
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|a Chapter 6. Molecular Basis of the Activity of Antibiotics of the Vancomycin Group:Guides for Peptide-Peptide Binding1 Introduction; 2 Stereoselectivity; 3 Peptide-peptide molecular recognition; 4 Approximate binding constants estimated for simple carboxylic acids; 5 A molecular interpretation of the binding process; Acknowledgements; References; Chapter 7. Recent Developments in the Use of Enzyme-Catalysed Reactions in Organic Synthesis; 1 Introduction; 2 Recent uses of hydrolase enzymes; 3 Recent uses of oxidoreductase enzymes
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|a Chirality in Drug Design and Synthesis.
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546 |
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|a English.
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650 |
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|a Pharmaceutical chemistry.
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650 |
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|a Drugs.
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650 |
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|a Organic compounds
|x Synthesis.
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|a Chemistry, Pharmaceutical
|0 (DNLM)D002626
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650 |
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2 |
|a Pharmaceutical Preparations
|0 (DNLM)D004364
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|a M�edicaments.
|0 (CaQQLa)201-0002990
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|a Compos�es organiques
|x Synth�ese.
|0 (CaQQLa)201-0020323
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|a Chimie pharmaceutique.
|0 (CaQQLa)201-0028674
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650 |
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|a Drugs
|2 fast
|0 (OCoLC)fst00898761
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650 |
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|a Organic compounds
|x Synthesis
|2 fast
|0 (OCoLC)fst01047668
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650 |
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|a Pharmaceutical chemistry
|2 fast
|0 (OCoLC)fst01060115
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653 |
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|a Drugs
|a Synthesis
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655 |
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2 |
|a Congress
|0 (DNLM)D016423
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|a proceedings (reports)
|2 aat
|0 (CStmoGRI)aatgf300027316
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|a Conference papers and proceedings
|2 fast
|0 (OCoLC)fst01423772
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|a Conference papers and proceedings.
|2 lcgft
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655 |
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|a Actes de congr�es.
|2 rvmgf
|0 (CaQQLa)RVMGF-000001049
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700 |
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|a Brown, C.
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776 |
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|i Print version:
|t Chirality in drug design and synthesis.
|d Academic, �1990
|w (OCoLC)22624397
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780121366704
|z Texto completo
|