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LEADER 00000cam a22000007a 4500
001 SCIDIR_ocn645898291
003 OCoLC
005 20231117033208.0
006 m o d
007 cr bn||||||abp
007 cr bn||||||ada
008 100702s1990 enkf ob 101 0 eng d
040 |a OCLCE  |b eng  |e pn  |c OCLCE  |d OCLCQ  |d UIU  |d OCLCF  |d YDXCP  |d IDEBK  |d E7B  |d OCLCQ  |d UKAHL  |d VLY  |d LUN  |d UKQUB  |d OCLCQ  |d OCLCO  |d COM  |d OCLCO  |d OCL  |d OCLCQ  |d OCLCO 
019 |a 608614011  |a 872652718  |a 1100878818  |a 1162414632  |a 1179424493  |a 1233319273 
020 |a 130648071X  |q (ebk) 
020 |a 9781306480710  |q (ebk) 
020 |a 9781483288246  |q (e-book) 
020 |a 1483288242 
020 |z 0121366707 
020 |z 9780121366704 
035 |a (OCoLC)645898291  |z (OCoLC)608614011  |z (OCoLC)872652718  |z (OCoLC)1100878818  |z (OCoLC)1162414632  |z (OCoLC)1179424493  |z (OCoLC)1233319273 
042 |a dlr 
050 4 |a QP517.C57  |b C45 1990 
082 0 4 |a 615.3  |2 20 
084 |a 44.42  |2 bcl 
245 0 0 |a Chirality in drug design and synthesis /  |c edited by C. Brown. 
260 |b Academic,  |c �1990. 
300 |a 1 online resource (xv, 243 pages, 4 unnumbered pages of plates) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
506 |3 Use copy  |f Restrictions unspecified  |2 star  |5 MiAaHDL 
533 |a Electronic reproduction.  |b [Place of publication not identified] :  |c HathiTrust Digital Library,  |d 2010.  |5 MiAaHDL 
538 |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.  |u http://purl.oclc.org/DLF/benchrepro0212  |5 MiAaHDL 
583 1 |a digitized  |c 2010  |h HathiTrust Digital Library  |l committed to preserve  |2 pda  |5 MiAaHDL 
588 0 |a Print version record. 
504 |a Includes bibliographical references and index. 
505 0 |a Front Cover; Dedication; Chirality in Drug Design and Synthesis; Copyright Page; Contributors; Foreword; Table of Contents; Introduction; Chapter 1. Chirality: Pharmacological Action and Drug Development; Introduction; 2 Terminology; 3 Enantioselectivity in pharmacological activity; 4 Enantioselectivity in pharmacodynamics resulting from differences in the pharmacokinetics of the enantiomers; 5 Conclusion; References; Chapter 2. Racemic Therapeutics-Problems all Along the Line; 1 Introduction; 2 Implications of chirality in bioactive agents; 3 Clinical pharmacology of racemic therapeutics 
505 8 |a 4 Ethical aspects of drug development, evaluation and use5 Non-information and disinformation in the field of chirality; 6 Racemates as drug combinations; 7 Perspectives; 8 Summary; References; Chapter 3. Chirality, Drug Metabolism and Action; 1 Introduction; 2 Stereochemistry and drug disposition; 3 Stereoselective metabolism and drug action; 4 Conclusions; References; Chapter 4. From Enzyme Mimics to Molecular Self-Assembly Processes; 1 Introduction; 2 A gift from nature; 3 Needs of enzyme mimics; 4 Serendipity yet again; 5 A chiral crown ether as a reagent 
505 8 |a 6 The same chiral crown ether as a catalyst7 Coordination through the second sphere; 8 Planned molecular self-assembly; 9 From host-guest chemistry to molecular assemblies; 10 Structure-directed synthesis; 11 The future; Acknowledgements; References; Chapter 5. Modelling of Drug-Receptor Interactions: Stereoselectivity of 5-Hydroxytryptamine and Dopamine Receptors in the Brain; 1 Introduction; 2 Interactions between L-ZGP and 8-OH DPAT; 3 Modelling of drug-receptor interactions; 4 DA D2-receptor agonists and antagonists; 5 5-HT1A-receptor agonists and antagonists; Acknowledgements; References 
505 8 |a Chapter 6. Molecular Basis of the Activity of Antibiotics of the Vancomycin Group:Guides for Peptide-Peptide Binding1 Introduction; 2 Stereoselectivity; 3 Peptide-peptide molecular recognition; 4 Approximate binding constants estimated for simple carboxylic acids; 5 A molecular interpretation of the binding process; Acknowledgements; References; Chapter 7. Recent Developments in the Use of Enzyme-Catalysed Reactions in Organic Synthesis; 1 Introduction; 2 Recent uses of hydrolase enzymes; 3 Recent uses of oxidoreductase enzymes 
520 |a Chirality in Drug Design and Synthesis. 
546 |a English. 
650 0 |a Pharmaceutical chemistry. 
650 0 |a Drugs. 
650 0 |a Organic compounds  |x Synthesis. 
650 2 |a Chemistry, Pharmaceutical  |0 (DNLM)D002626 
650 2 |a Pharmaceutical Preparations  |0 (DNLM)D004364 
650 6 |a M�edicaments.  |0 (CaQQLa)201-0002990 
650 6 |a Compos�es organiques  |x Synth�ese.  |0 (CaQQLa)201-0020323 
650 6 |a Chimie pharmaceutique.  |0 (CaQQLa)201-0028674 
650 7 |a Drugs  |2 fast  |0 (OCoLC)fst00898761 
650 7 |a Organic compounds  |x Synthesis  |2 fast  |0 (OCoLC)fst01047668 
650 7 |a Pharmaceutical chemistry  |2 fast  |0 (OCoLC)fst01060115 
653 |a Drugs  |a Synthesis 
655 2 |a Congress  |0 (DNLM)D016423 
655 7 |a proceedings (reports)  |2 aat  |0 (CStmoGRI)aatgf300027316 
655 7 |a Conference papers and proceedings  |2 fast  |0 (OCoLC)fst01423772 
655 7 |a Conference papers and proceedings.  |2 lcgft 
655 7 |a Actes de congr�es.  |2 rvmgf  |0 (CaQQLa)RVMGF-000001049 
700 1 |a Brown, C. 
776 0 8 |i Print version:  |t Chirality in drug design and synthesis.  |d Academic, �1990  |w (OCoLC)22624397 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780121366704  |z Texto completo