Cholesterol metabolism, LDL, and the LDL receptor /

Cholesterol Metabolism, LDL, and the LDL Receptor focuses on the cholesterol biochemistry and lipoprotein metabolism. This book is organized into 10 chapters that describe the coordinated actions of three regulated processes, namely, the intracellular synthesis of cholesterol, its esterification by...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Myant, N. B.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1990.
Temas:
Low density lipoproteins.
Low density lipoproteins > Receptors.
Cholesterol > Metabolism.
Cholesterol > metabolism
Cholesterol, LDL > metabolism
Receptors, LDL > physiology
Lipoproteins, LDL
Lipoprot�eines de basse densit�e.
Lipoprot�eines de basse densit�e > R�ecepteurs.
Cholest�erol > M�etabolisme.
Cholesterol > Metabolism
Low density lipoproteins
Low-density-Lipoproteine
Stoffwechsel
Apolipoproteine
Cholesterinstoffwechsel
Lipids > Metabolism
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Cholesterol Metabolism, LDL, and the LDL Receptor; Copyright Page; Table of Contents; Foreword: Simplifying Cholesterol Metabolism; Preface; Acknowledgments; Chapter 1 . The LDL Receptor in Perspective; Chapter 2. Cholesterol in Animal Tissues; I. Functions and Distribution; II. Sources of Cholesterol in Different Tissues; III. Measurement of Whole-Body Synthesis of Cholestero l; Chapter 3. HMG-CoA Reductase; I. The Rate-Limiting Step in Cholesterol Biosynthesis; II. Composition, Structure, and Orientation; III. The HMG-CoA Reductase Gene and Its mRNA.
  • IV. Somatic-Cell Mutants in the Study of Cholesterol MetabolismV. The Regulation of HMG-CoA Reductase; Chapter 4. Acyl-CoA: Cholesterol Acyltransferase; I. Biological Functions; II. Properties and Methods of Assay; III. ACAT and the Metabolism of Intracellular Cholesteryl Esters; IV. Regulation of ACAT; References; Chapter 5. LDL: Physical and Chemical Characteristics; I. Composition and Physical Characteristics; II. Structure; III. Heterogeneity and Genetic Polymorphism; References; Chapter 6. Apolipoprotein B (apoB); I. LDL ApoB: Definition and Some Properties.
  • II. ApoB Species in Human PlasmaIII. Composition and Structure of ApoB-100; IV. Lp(a): A Lipoprotein Containing ApoB-100; V. The LDL-Receptor-Binding Site on ApoB; VI. The ApoB Gene and Its mRNA; VII. Polymorphism in the Human ApoB Gene; VIII. Polymorphism in the ApoB Gene in Animals; IX. ApoB (Arg3 5 0 0-�Gln): A Rare Variant; X. Mutations Causing Absence or Deficiency of Plasma ApoB; References; Chapter 7. LDL: Origin and Metabolism; I. The Production of LDL; II. LDL Catabolism in Vivo; References; Chapter 8. The LDL Receptor: Biochemistry and Cell Biology; I. Historical Background.
  • II. Surface Binding and Intracellular Degradation of LDLIII. LDL Receptors in Nonfibroblast Cells; IV. Effects of Growth Factors and Hormones in Vitro; References; Chapter 9. The LDL Receptor: Structure, Biosynthesis, and Molecular Genetics; I. The Route to Isolation of the Human Receptor and Its Gene; II. The Normal LDL Receptor; III. The LDL-Receptor Gene and Its Message; IV. Regulation of Expression of the Receptor Gene; V. Natural Mutations at the Receptor Locus; VI. Somatic-Cell Mutations; VII. Polymorphism in the LDL-Receptor Gene; VIII. Evolutionary Aspects of the Receptor Gene.

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