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Development of anti-asthma drugs /
Development of Anti-Asthma Drugs reviews existing asthma treatments and novel approaches currently under investigation, in the context of their mode of action and clinical effectiveness, in the hope that this might lead to a greater understanding of the factors involved in the expression of the dise...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London ; Boston :
Butterworths,
1984.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Development of Anti-Asthma Drugs; Copyright Page; Preface; Contributors; Table of Contents; Introduction; Part 1: Asthma
- the nature of the disease; Chapter 1. Asthma-the nature of the disease; Definition-what is asthma?; Natural history; Epidemiology; Pathological mechanisms; Part 2: Mediators; Chapter 2. Histamine; Introduction; Histamine release; Actions of histamine; Concluding remarks; Chapter 3. Leukotrienes; Introduction; Structure, formation and metabolism; Biological activities of the leukotrienes; Conclusions; Chapter 4. Platelet-activating factor; Introduction
- Historical overview of platelet-activating factorStructure and metabolism of PAF; PAF production in inflammation; PAF-induced platelet stimulation; Other inflammatory effects of PAF; Physiology; Effects on smooth muscle; Effects of vascular permeability; Pharmacological modulation; Conclusion; Chapter 5. Eosinophils and neutrophils; Introduction; General properties of eosinophils and neutrophils; Allergy and the eosinophil; Allergy and the neutrophil; Inflammatory cells and the progression of asthma; Corticosteroids, eosinophils and neutrophils; Summary; Chapter 6. Acetylcholine; Introduction
- Acetylcholine as a neurotransmitterThe cholinergic nervous system in asthma; Summary; Part 3: Pharmacological approaches; Section 1: Competitive antagonists; Chapter 7. Hi antihistamines Noemi Eiser; Introduction; Effects of H!-receptor antagonists when given to asthmatics by various routes; Conclusions; Chapter 8. SRS-A antagonists; Development of FPL 55712; Biological effects of FPL 55712; Characterization of leukotriene receptors; Other antagonists of SRS-A; Clinical evaluation of SRS-A antagonists; Prospects; Chapter 9. Anti-cholinergic drugs