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Bone cancer : progression and therapeutic approaches /
The epidemiological and clinical importance of bone metastasis has long been recognized, but the past decade has seen an explosion in the fields of bone biology and bone cancer research. This period of time has been marked by a number of key discoveries that have led to the opening up of entirely ne...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston ; London :
Academic,
�2010.
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| Edición: | 1st ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Section 1: Introduction
- Genetic control, frequencies and epidemiology of bone cancers
- The incidence and progression of metastatic bone lesions
- Section 2: Bone microenvironment and bone cancer
- Bone microenvironment and tumor growth
- Osteoblast Differentiation and Cell Signalling
- Osteoclast Differentiation and Function
- Cytokines in bone remodeling and bone tumors
- Proteases and bone tumors
- therapeutic approaches
- Section 3: Bone markers
- Early bone metastasis
- Bone remodeling markers and bone cancer
- Proteomic of bone cancers
- Genomic Alterations in Bone Tumors
- Biology of bone tumors and new diagnostic tools
- Gene profiling of osteosarcoma
- Molecular pathology of osteosarcoma
- Histopathology of prostate and breast metastases
- Technical aspects: how do we best prepare bone samples for proper histological analysis?
- Section 4: Myeloma, odontogenic tumors and bone metastases
- Multiple myeloma bone diseases
- Osteolytic lesions
- Bone metastases of prostatic cancer
- Bone metastases of breast cancer
- Section 5: Primary bone tumors
- Osteosarcoma and osteoblasts: diagnosis and therapy
- Ewing sarcoma family of tumors: diagnosis and therapy
- Non-surgical treatment of chondrosarcoma: diagnosis and therapy
- Chondrosarcoma of bone: diagnosis and therapy
- Osteoclast-rich lesions of bone: diagnosis and therapy
- Section 6: Imaging of bone cancers
- Interventional Radiologic Techniques
- Imaging of bone metastases
- Diagnosis of bone metastases
- Section 7: Pain control in bone cancers
- Pain control with radiotherapy
- Mechanisms and management of bone cancer pain
- Malignant skeletal pain
- Section 8: New therapeutic advances of bone cancers
- Primary bone tumors and novel therapeutic approaches
- Cytokine gene therapy in bone remodeling
- Bisphosphonates
- Multi-targeted approach
- RANKL and targeted therapy
- Apoptosis and drug resistance.