Essentials of stem cell biology /

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First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined ef...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Lanza, Robert, 1956-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, CA ; London, UK : Academic Press, 2009.
Edición:2nd ed.
Temas:
Stem cells > Textbooks.
Stem cells.
Tissue engineering.
Stem Cells
Embryo Research
Biomedical Research
Tissue Engineering
Cellules souches.
G�enie tissulaire.
Tissue engineering
Stem cells
Textbooks
Textbooks.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • FOREWORD
  • Why Stem Cell Research?
  • A New Path?{ Induced Pluripotent Stem Cells
  • Embryonic Stem Cells Versus Adult Stem Cells
  • 'Stemness': Definitions, Criteria and Standards
  • PART ONE
  • INTRODUCTION TO STEM CELLS
  • 1. Present Perspective and Future Challenges
  • 2. Embryonic Stem Cells in Perspective
  • 3. The Development of Epithelial Stem Cell Concepts
  • 4. The Advent of Direct Reprogramming
  • 5. Clinical Translation of Stem Cells
  • PART TWO
  • BASIC BIOLOGY/MECHANISMS
  • 6. Molecular Basis of Pluripotency
  • 7. Stem Cell Niches
  • 8. Mechanisms of Stem Cell Self-Renewal
  • 9. Cell Cycle Regulators in Stem Cells
  • 10. Epigenetic Mechanisms of Cellular Memory
  • 11. Cell Fusion and the Differentiated State
  • 12. How Cells Change Their Phenotype
  • PART THREE
  • TISSUE AND ORGAN DEVELOPMENT
  • 13. Differentiation in Early Development
  • 14. Primordial Germ Cells in Mouse and Human
  • 15. Stem Cells in Extraembryonic Lineages
  • 16. Amniotic Fluid Derived Pluripotent Cells
  • 17. Cord Blood Stem Cells
  • 18. Neurogenesis in the Vertebrate Embryo
  • 19. The Nervous System
  • 20. Neuronal Progenitors in the Adult Brain
  • 21. Sensory Epithelium of the Eye and Ear
  • 22. Epithelial Skin Stem Cells
  • 23. The Ontogeny of the Hematopoietic System
  • 24. Hematopoietic Stem Cells
  • 25. Red Blood Cells
  • 26. Cell Differentiation in the Skeleton
  • 27. Vascular Progenitor Cells
  • 28. Multipotent Adult Progenitor Cells
  • 29. Mesenchymal Stem Cells
  • 30. Skeletal Muscle Stem Cells
  • 31. Stem Cells and the Regenerating Heart
  • 32. Potential of ES Cell Differentiation Culture for Vascular Biology
  • 33. Cell Lineages and Stem Cells in the Kidney
  • 34. Adult Liver Stem Cells
  • 35. Pancreatic Stem Cells
  • 36. Stem Cells in the Gastrointestinal Tract
  • 37. Stem Cells in the Lung
  • PART FOUR
  • METHODS
  • 38. Generation of Induced Pluripotent Stem Cells
  • 39. Characteristics and Characterization of Pluripotent Stem Cells
  • 40. Isolation and Maintenance of Murine Embryonic Stem Cells
  • 41. Isolation, Characterization, and Maintenance of Primate ES Cells
  • 42. Approaches for Derivation and Maintenance of Human ES cells:
  • Detailed Procedures and Alternatives
  • 43. Derivation and Differentiation of Human EG Cells
  • 44. Growth Factors & the Serum-Free Culture of Human Pluripotent Stem Cells
  • 45. Feeder-Free Culture
  • 46. Genetic Manipulation of Human Embryonic Stem Cells
  • 47. Homologous Recombination in Human Embryonic Stem Cells
  • 48. Surface Antigen Markers
  • 49. Lineage Marking
  • 50. Genomic Reprogramming
  • 51. Isolation and Characterization of Hematopoietic Stem Cells
  • 52. Microarray Analysis of Stem Cells and Differentiation
  • 53. Zebrafish and Stem Cell Research
  • PART FIVE
  • APPLICATIONS
  • 54. Cancer Stem Cells
  • 55. Neural Stem Cells: Therapeutic Applications in Neurodegenerative Diseases
  • 56. Spinal Cord Injury
  • 57. Use of Embryonic Stem Cells to Treat Heart Disease
  • 58. Insulin-Producing Cells Derived from Stem Cells: A Potential Treatment for Diabetes
  • 59. Burns and Skin Ulcers 978-0-12-370465-8
  • 60. Stem Cells and Heart Disease
  • 61. Stem Cells for the Treatment of Muscular Dystropy
  • 62. Skin Regeneration
  • 63. Orthopaedic Applications of Stem Cells
  • 64. Embryonic Stem Cells in Tissue Engineering
  • 65. Adult Stem Cells in Tissue Engineering
  • 66. Stem Cell Gene Therapy
  • PART SIX
  • REGULATION AND ETHICS
  • 67. Ethical Considerations
  • 68. Religious Considerations
  • 69. Regulatory Considerations
  • 70. It��s Not About Curiosity, It��s About Cures
  • Epilogue: Concluding Statement.
  • Introduction to stem cells
  • Basic biology/mechanisms
  • Tissue and organ development
  • Methods
  • Applications
  • Regulation and ethics.

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