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Regulators and effectors of small GTPases : Rho family /
The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission....
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, California :
Elsevier Academic Press,
�2006.
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| Colección: | Methods in enzymology ;
v. 406. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
| Sumario: | The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). |
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| Descripción Física: | 1 online resource (xliii, 798 pages, 24 unnumbered pages of plates) : illustrations |
| Bibliografía: | Includes bibliographical references and indexes. |
| ISBN: | 0080479391 9780080479392 0121828115 9780121828110 1281050369 9781281050366 9786611050368 6611050361 |
| ISSN: | 0076-6879 ; |